Write the equation for the following steps. The reaction of benzaldehyde with a molecule of acetone...
Write the equation for the following steps.
The reaction of benzaldehyde with a molecule of acetone catalysed
by NaOH to form an aldol addition product.
The spontaneous loss of water from the aldol to form the aldol
condensation product.
The reaction of the resulting product with a second molecule of
benzaldehyde, catalysed by NaOH, to form another aldol addition
product.
The spontaneous loss of water from the aldol to form the final
aldol condensation product.
The overall equation.
Write the side reaction of the base catalysed reaction of acetone with itself to form an aldol addition product and then the subsequent loss of water to form the aldol condensation product.
Homework Answers
Add Answer to:
Write the equation for the following steps.
The reaction of benzaldehyde with a molecule of acetone...
Since the speed of the aldol condensation of acetone and benzaldehyde depends on the concentration of...
Since the speed of the aldol condensation of acetone and benzaldehyde depends on the concentration of both organic reagents and the base, indicate which of the steps of the total reaction is the determining step of the rapidity. Use equations.
Please write out a reaction aldol mechanism for the reaction of benzaldehyde and acetophenone and Naoh...
Please write out a reaction aldol mechanism for the reaction of benzaldehyde and acetophenone and Naoh with p-anisaldehyde to form a chalcone
Aldol condensation reaction requires the loss of a molecule of water and hence performing the reaction...
Aldol condensation reaction requires the loss of a molecule of water and hence performing the reaction in water should disfavor this reversible dehydration from occurring. Based on your observations during the laboratory, provide a reasonable explanation as to why the condensation product is observed at all? (Note: Heat accelerates the reaction in reach equilibrium but DOES NOT directly favor the Aldol Condensation product).
Look up the pKa for water and acetone and write these values in the boxes below...
Look up the pKa for water and acetone and write these values in the boxes below each molecule in the provided reaction scheme. Considering this information, which of the three reaction arrows best describes enolate formation? Considering the direction of the equilibrium from question 4, what do you think is the driving force for the aldol condensation?
Write a mechanism for the acid–catalysed condensation of acetone. Looking at the structure of this product, and of ethyl...
Write a mechanism for the acid–catalysed condensation of acetone. Looking at the structure of this product, and of ethylenediamine, suggest how the macrocyclic ligand might form. Can you provide answer for this question, the macro ligand was prepared from ethylenediamine, 50% tetrafluoroboric acid.
Make sure the reaction table described above is completed in your notebook.
Prelab questions:1. Make sure the reaction table described above is completed in your notebook.2. Two benzaldehyde molecules combine with one acetone molecule in this aldol reaction. If someone uses 5.0 mL of benzaldehyde and 2.5 mL of acetone to try to improve the yield of product, is this the correct ratio of molecules so that there is no excess? Why or why not?The Aldol Reaction: Synthesis of DibenzalacetonePurpose: Introduce the student to the hands-on chemistry of carbonyl condensations.Warning: Dispose of...
Provide a detailed, step-by-step mechanism for the base-catalyzed (-OH) reaction between two molecules of acetone to...
Provide a detailed, step-by-step mechanism for the base-catalyzed (-OH) reaction between two molecules of acetone to form the Aldol addition product.
What reagent loses the alpha hydrogen to become the nucleophilic carbanion? Aldol Reaction: Synthesis of trans,...
What reagent loses the alpha hydrogen to become the nucleophilic
carbanion?
Aldol Reaction: Synthesis of trans, trans-1,5-Diphenyl-1,4. pentadien-3-one (Dibenzalacetone) In the present experiment, you will be performing a practical Aldol reaction using benzaldehyde acetone. The final condensed Aldol product (trans, trans-1,5-diphenyl-1,4-pentadien-3-one) an extensive conjugation system The first condensed Aldol benzaldehyde and acetone. The final condensed Aldol product will form when the initial Aldol product reacts with benzaldehyde resulting in 2:1 mole ratio of benzaldehyde and acetone. Addition Aldol products are...
1. The reaction web includes most of the reactions of enolates we have studied. The products...
1. The reaction web includes most of the reactions of enolates we have studied. The products of these reactions can be treated with other reagents to generate new functionality - think synthesis! Make up your own examples - e.g. What if you treated compound D with CH,MgBr? In the table, summarize the types of products produced from these reactions. CH3 MgBr acid quench acid quench NaOH, H2O EIO OEt acid quench acid quench acid quench D LIAIHA acid quench acid...
#105 of Aldol Condensation What would be the major product isolated from the aldol reaction of acetone (with base) and a...
#105 of Aldol Condensation What would be the major product isolated from the aldol reaction of acetone (with base) and acetophenone, with a cold water workup in the second step? Select one: a. 4-hydroxy-1-phenyl-1-pentanone b. 1-phenyl-3-penten-1-one c. 3-hydroxy-4-methyl-4-phenyl-2-butanone d. 4-methyl-4-phenyl-3-buten-2-one e. 4-hydroxy-4-methyl-4-phenyl-2-butanone
Look up the pKa for water and acetone and write these values in the boxes below each molecule in the provided reaction scheme. Considering this information, which of the three reaction arrows best describes enolate formation? Considering the direction of the equilibrium from question 4, what do you think is the driving force for the aldol condensation?
Provide a detailed, step-by-step mechanism for the base-catalyzed (-OH) reaction between two molecules of acetone to form the Aldol addition product.
What reagent loses the alpha hydrogen to become the nucleophilic
carbanion?
Aldol Reaction: Synthesis of trans, trans-1,5-Diphenyl-1,4. pentadien-3-one (Dibenzalacetone) In the present experiment, you will be performing a practical Aldol reaction using benzaldehyde acetone. The final condensed Aldol product (trans, trans-1,5-diphenyl-1,4-pentadien-3-one) an extensive conjugation system The first condensed Aldol benzaldehyde and acetone. The final condensed Aldol product will form when the initial Aldol product reacts with benzaldehyde resulting in 2:1 mole ratio of benzaldehyde and acetone. Addition Aldol products are...
1. The reaction web includes most of the reactions of enolates we have studied. The products of these reactions can be treated with other reagents to generate new functionality - think synthesis! Make up your own examples - e.g. What if you treated compound D with CH,MgBr? In the table, summarize the types of products produced from these reactions. CH3 MgBr acid quench acid quench NaOH, H2O EIO OEt acid quench acid quench acid quench D LIAIHA acid quench acid...
Most questions answered within 3 hours.
-
In the following concepts of economics provide a
discussion of the meaning as well as the...
asked 1 minute ago -
The table below shows the number of deaths in the U.S. in a year
due to...
asked 14 minutes ago -
Suppose we now care about the long run decisions of a firm that
has a production...
asked 14 minutes ago -
Two tugboats pull a disabled supertanker. Each tug exerts a
constant force of 1.20×106 N ,...
asked 25 minutes ago -
Outline the major trends shaping franchising
asked 32 minutes ago -
The solubility of magnesium phosphate is 2.27 × 10-3 g/1.0 L of
solution. What is the...
asked 32 minutes ago -
. Pendulum Inc. uses moving-average costing. Its 20X8
ending inventory is 900 units that have an...
asked 30 minutes ago -
This is a question about selling :
Abby has been working with a couple for a...
asked 34 minutes ago -
For water, Kf = 1.86 °C∙kg/mole, Kb = 0.52 °C∙kg/mole and
density = 1.00 g/mL. Calculate...
asked 46 minutes ago -
Why in 100 words Social Darwinism have such broad appeal? please
type
asked 47 minutes ago -
Should we be concerned about corporations that just don't seem
to care if sexual harassment occurs?...
asked 51 minutes ago -
Plese use R-Studio to answer this question.
qbinom(p, size, prob) gives the smallest x value so...
asked 51 minutes ago