In our lab we synthesized guaifenesin using Williamson ether synthesis. What would be an example of...
In our lab we synthesized guaifenesin using Williamson ether synthesis. What would be an example of another method of ether synthesis? Illustrate it with drawn reaction scheme and describe it in a few sentences.
Homework Answers
The process will be alkoxymercuration-demercuration.
Add Answer to:
In our lab we synthesized guaifenesin using Williamson ether
synthesis. What would be an example of...
Williamson Ether Synthesis of Guaifenesin Starting Materials - 2-methoxyphenol (guaiacol): 550 uL - 3-chloro-1,2-propanediol: 500 uL...
Williamson Ether Synthesis of Guaifenesin Starting Materials - 2-methoxyphenol (guaiacol): 550 uL - 3-chloro-1,2-propanediol: 500 uL - Sodium hydroxide: 1 mL of 6M Product - Guaifenesin What is the yield expected in (g) and (mmoles)?
How would you prepare benzyl methyl ether using a Williamson ether synthesis? The list of reagents...
How would you prepare benzyl methyl ether using a Williamson ether synthesis? The list of reagents to choose from are: 2-Chloro-norborane, Benzyl chloride, 2-Chloro-2-methylpropane, 4-Chloro-1-butanol, and Chlorobutane. I was reading online and it kept mentioning SN2 reactions, using an alcohol, and an alkyl halide for the synthesis. My guess would be using Benzyl Chloride and another one with an OH attached, but I could be completely wrong. Please help and explain by showing the reaction mechanism. Thank you so much!...
e) Typically. Williamson ether synthesis is conducted using Na, a very strong base in the reaction...
e) Typically. Williamson ether synthesis is conducted using Na, a very strong base in the reaction in d. however, the Williamson ether synthesis was accomplished with K.CO a much weaker base Why can K.CO, be used for this Williamson ether synthesis? n What general type of reaction is occurring here? g) Predict the reagents, then propose a mechanism (Hint: don't reduce the ester) OCH,
This is a williamson ether synthesis SN2 reaction. what are the complete mechanisms of this reaction,...
This is a williamson ether synthesis SN2 reaction. what are
the complete mechanisms of this reaction, with the intermediates
included?
MLNVILI SYNTHESIS OF 2-BUTOXYNAPHTHALENE OH 1. NaOH, ETOH 2. n-BuBr DISCUSSION: Nucleophilic substitution reaction is a frequently used method to convert one functional group into another. A nucleophile is mixed with an electrophile and the nucleophile replaces the leaving group to produce a new compound. In this experiment, a weak nucleophile (2-naphthol) is converted into a strong nucleophile. Then this...
Could the Williamson Ether synthesis be carried out using any type of alkyl halide? Why/why not....
Could the Williamson Ether synthesis be carried out using any type of alkyl halide? Why/why not. Draw the mechanism for the Williamson Ether reaction using bromoethane and t-butyl bromide and relate it to your answer.
The ether shown can be prepared using a Williamson ether synthesis; that is, by reacting an...
The ether shown can be prepared using a Williamson ether synthesis; that is, by reacting an alkoxide ion with an alkyl halide. Draw the alkoxide ion and alkyl bromide that you would combine to make the ether with the highest possible yield. You may omit the metal cation counterion that accompanies the alkoxide ion for the purposes of this question. Include all lone pairs and nonzero formal charges. 1 stattomat
4) Briefly explain why the following molecule cannot be produced using Williamson ether synthesis. 4 pts...
4) Briefly explain why the following molecule cannot be produced using Williamson ether synthesis. 4 pts Note: a complete answer will illustrate the two theoretical William ether synthetic pathways that could be used to synthesis the product (1 pt each) and explain why each pathway would not yield the desired product (1 pt each). Bonus: Provide a different synthetic pathway that produces the ether shown above. (I could do it in a single step!). (bonus 2 pts).
Why is EtOH not ideal for the Williamson ether synthesis? What would be a better solvent...
Why is EtOH not ideal for the Williamson ether synthesis? What would be a better solvent choice? Why isn't the better solvent choice used on a large industrial scale? Consider the cost and waste disposal.
Help with question #4. The reaction can be taken from #1 . wILLIAMSON ETHER SYNTHESS: PREPARAT?ON...
Help with question #4. The reaction can be taken from #1
. wILLIAMSON ETHER SYNTHESS: PREPARAT?ON OF PHENACETN FROM ACETAMINOPHEN LA8 10 LAB 10 ? NAME DATE LAB SECTION Answer the following questions in the pre-lab section of your notebook. 1. Draw the mechanism for the reaction between phenacetin, potassium carbonate, and 2. List three limitations of the Williamson ether synthesis and explain how our choice of 3. What is the purpose of the rotary evaporator? What other technique that...
Need help, numbers 3-6 please show work. and fill out table of chemicals for all chemical...
Need help, numbers 3-6 please show work. and fill out table of
chemicals for all chemical used.
calculate mmol in the table as well show work please
and each of these must be listed in its own row. There are 10 column headings: IUPAC name OR common name, structure, CAS number (Chemical Abstract Service number) molecular mass, melting point (if applicable), boiling point (if applicable), solubility (in water, if applicable), density, amounts to be used in the experiment, and the...
e) Typically. Williamson ether synthesis is conducted using Na, a very strong base in the reaction in d. however, the Williamson ether synthesis was accomplished with K.CO a much weaker base Why can K.CO, be used for this Williamson ether synthesis? n What general type of reaction is occurring here? g) Predict the reagents, then propose a mechanism (Hint: don't reduce the ester) OCH,
This is a williamson ether synthesis SN2 reaction. what are
the complete mechanisms of this reaction, with the intermediates
included?
MLNVILI SYNTHESIS OF 2-BUTOXYNAPHTHALENE OH 1. NaOH, ETOH 2. n-BuBr DISCUSSION: Nucleophilic substitution reaction is a frequently used method to convert one functional group into another. A nucleophile is mixed with an electrophile and the nucleophile replaces the leaving group to produce a new compound. In this experiment, a weak nucleophile (2-naphthol) is converted into a strong nucleophile. Then this...
The ether shown can be prepared using a Williamson ether synthesis; that is, by reacting an alkoxide ion with an alkyl halide. Draw the alkoxide ion and alkyl bromide that you would combine to make the ether with the highest possible yield. You may omit the metal cation counterion that accompanies the alkoxide ion for the purposes of this question. Include all lone pairs and nonzero formal charges. 1 stattomat
4) Briefly explain why the following molecule cannot be produced using Williamson ether synthesis. 4 pts Note: a complete answer will illustrate the two theoretical William ether synthetic pathways that could be used to synthesis the product (1 pt each) and explain why each pathway would not yield the desired product (1 pt each). Bonus: Provide a different synthetic pathway that produces the ether shown above. (I could do it in a single step!). (bonus 2 pts).
Help with question #4. The reaction can be taken from #1
. wILLIAMSON ETHER SYNTHESS: PREPARAT?ON OF PHENACETN FROM ACETAMINOPHEN LA8 10 LAB 10 ? NAME DATE LAB SECTION Answer the following questions in the pre-lab section of your notebook. 1. Draw the mechanism for the reaction between phenacetin, potassium carbonate, and 2. List three limitations of the Williamson ether synthesis and explain how our choice of 3. What is the purpose of the rotary evaporator? What other technique that...
Need help, numbers 3-6 please show work. and fill out table of
chemicals for all chemical used.
calculate mmol in the table as well show work please
and each of these must be listed in its own row. There are 10 column headings: IUPAC name OR common name, structure, CAS number (Chemical Abstract Service number) molecular mass, melting point (if applicable), boiling point (if applicable), solubility (in water, if applicable), density, amounts to be used in the experiment, and the...
Most questions answered within 3 hours.
-
For a voltaic cell based on the reaction below, which statement
is correct?
Zn(s)+2H+(aq)→Zn2+(aq)+H2(g)
Zn2+(aq) is...
asked 14 seconds ago -
For the balanced reaction: CaCl2 (aq) + Na2CO3 (aq) -> CaCO3
(s) + 2 NaCl (aq),...
asked 10 minutes ago -
1. If ln(x)=ln(x)= -0.2 , what does xx equal? Round
your answer to three significant figures. The...
asked 7 minutes ago -
what is the current research being done on the hexokinase
enzyme?
asked 13 minutes ago -
An incline weighing 1,106 kg with its passengers travels uphill
800 meters on a 30 degree...
asked 13 minutes ago -
Let’s assume you want to retire with $1,000,000 in your
investment portfolio. Given that your investment...
asked 13 minutes ago -
profit motivation is one of the biggest differences between
public and private organizations. what about resource...
asked 12 minutes ago -
Test the hypothesis using P-value approach. Be sure to verify
the requirements of the test.
H0:...
asked 15 minutes ago -
Balance the following oxidation-reduction equations using redox
methods:
Cu + H+ --------> Cu+ +
H2
asked 16 minutes ago -
Baltimore Manufacturing had a Work in Process balance of $84,000
on January 1, 2018. The year...
asked 20 minutes ago -
Need help converting into sql language.
How many players from each town served on the committee...
asked 32 minutes ago -
A professor needs to assign 15 teaching assistants to the course
STATISTICS 101. There are 40...
asked 34 minutes ago