Question

reaction of a ........with an alkyl halide, 19. The Williamson ether synthesis consists of an alkyl sulfonate, or alkyl sulfate. A SNI, sodium chloride B. SN2, sodium alkoxide C. El sodium chloride DE2, sodium chloride 20. Which of the following statements is not true regarding oxymersuration- demecution? A. They are regioselective reactions. B. The net reaction does not follow Markoynikey's Rule in its original statement. C. The reducing reagent NaBH, is involved in demersuration D. Water is required for the oxymersurati step. 21. In hydroboration followed by oxidation of the compound below, which group will be linked to carbon one of the structure below? CH,CH:CH-CH2 A. H В. В COH D. CHO 22. Reaction of a primary alcohol with SOCI: produces A. alkylchloride B. alkyne C. carboxylic acid D. alkane 23. The reagent borane in tetrahydrofuran (THF) contains which compound? A. HBO, B. BH 827 words C. Hg(2)

Answer 1

9 Wallinman ether Synthesis In Alliam on elhex им е нія, од отдаль һама a koulde ( de protomated alcohol) to me, an organphalide rency with alde deprotonated alcohol) to form ether. It involves, generally the reaction of an altosude im with primary alkyl halido via an Swa mechanism Grample: CaHSOH + Colts-cu NaOH, GHS-O-GH5 • Mechanism. In first step base (NaOH) abstracts the proton from alcohol Cote-0-H + OHNa G H50 Na + H₂O (Sodium ethoxide) ) In an SNP mechanism, there in a backside attack of an electrophile by a nucleophile & it Oclours in a concerted mechanism. Caso + Ehsal GHS-O-GH5 (Nucleophuile) (electroplvile) D O ry meruration de mercuration r'n:- Alkene hydrection using the only mercuration-demeruuration gation pathway reliably produces the Markownikov proderet without carbocation rearrangement OH ) H (DA)Ha0, THE a) Na 8H4,00 Dve mercuration - demerturation is a two Ateb pathury atured to produce alcohols. The rem proceeds in a Markovnikov manner & in stereo s beu ficcanti addition, not regis elective

Mechowni The ni elettront of double bon me neletion of double bond form a bond to Mercury while the lone pair on the mercury, simultaneously bonds to the other vinyl carbon creating a mercurium in bridge DAC OA A watey molecule reach with the most substituted carbon to open the mercurium ion bridge. HOAC - M y Na Afy/pP G+ OA OH M₂ - The final step of the sun is the reduction of the 19 organo meruiry intermediate with sodium bord hy duide linder basic conditions Hydro boration gelmi- This is the two step pathway used to produce alcohols. The grohn broceed in an Anti-Markovnikov manner, where the hydrogen ( from BH₂ Or BHR2) attaches to the more substituted carbon boron attaches to the least substit Forchem in the alkene double bond The hydroboration e on the same face of the double bond, leads can stereo chemistoy & BH₂ T BH₂ face of to take place on the same eroxide (H22) In the ocidation part, the hydrogen peroxide forms hydrogen peroxide ion in the presence of bay -

Hogti + oH 4-0-0® + H20 1 The in attacks to the boron intermediate, followed by the rearrangement yields final alcohor product . neo-07 н Bн, H rangement Rearrangement 0-BH2 + 8H • OH) Hydoo lysis (New carbon- oxygen bond formed). • 3 Rh of primary alcohol with solla :- An alcohol & thionyl chloride reach of produces an alkyl chloride. The by products here are HU & SO2 gas. OH sol e + Hupt sopp