Question

2. Predict the product and draw the mechanism for the Grignard reaction shown in the video. Show all electron pairs that participate in the reaction, electron flow arrows, and intermediates. Write a paragraph describing what is happening during the mechanism. MgBr Ph H 2.NH.Cl(aq) 3. Why must this reaction be done in two steps? (In other words, what would happen in you mixed the carbonyl. Grignard reagent, and the aqueous ammonium chloride all together?) 4. In this reaction NHCI was used instead of a stronger acid, such as H,SO, or HCL. What would have happened to the resulting alcohol if a stronger acid was used? 5. What is the purpose of adding I, to the reaction? 6. During the purification step anhydrous MgSO, was added. What is the purpose of adding this reagent? 7. Write a paragraph explaining how you could use IR and NMR to show that the Grignard reaction proceeded as you predicted in (NMR data for the product is provided in the pdf of the lab on Jove)

Answer 1

Solution: - ph F Cik Borming S 1 + 1 pha Ph - Step- Int1 NHL Step. 2 ph 1 + Ho my Br. ally I In step. 1 vingt magnesium bromide attack on x-13 unsaturated aldehyde ae cinnamaldehyde by 1, 2 lamaldehyde by to form 1, 2 addition ant-1. a Then the Int- quenched with aq NM 4 cl give alcohol and My Br (OH) by-product- ② If we mix all reagent together, In this case &t allyl- magnesium bromide will react with aq Nhach and get quench- a my Br+ aq NHAC a t my Br COH) under go (4) If stronger acid used in quenching the alcohol elimination in Hasou OH ph san Hasoy ph M . and in Hell we will get mixt use of ph Hal , Ph vitph 6 Addition of Iz is to help remore and no on the mg. Removing ngo allows for my and the aryl halide t OH surface of the alkyl or any REDMI NOTE 5 PRO in contandt and react.