4. In each case below identify: (a) the leaving group (b) the nucleophile, (c) and if...
4. In each case below identify: (a) the leaving group (b) the nucleophile, (c) and if the reaction is an Syl reaction or Sn2 reaction. (d) Draw the products of the following substitution reactions. NaSH DMSO MeOH H- Br NaCN DMF
I nucleophile substitution. 7.8 Which is the better leaving group in each pair? a a, b, NH, NH, C. HẠO, HAS 7.9 Which molecules contain good leaving groups? a. CH CH.CH,Br b . CH,CH,CH,OH . CH.CH,OH, d. CH.CH Does the equilibrium favor the reactants or products in each substitution reaction? a. CH,CH-NH, + Br -- CH,CHBr + NH b. n + ON ~ ON + r 7.6 Identify the nucleophile and leaving group and draw the products of each reaction...
(S)-3-Chlorooctane m DMSO S SN2 Factors Nucleophile Strength Leaving Group Solvent d) Cla . NaBrº DMSO Syl SN2 Factors Nucleophile Strength Leaving Group Solvent SN1 and SN2 Reactions 1. For each of the following reactions • Provide a complete detailed mechanism and predict the products. Indicate if the reaction proceeds via a Snl or Sn2 mechanism • Include the specific stereochemistry where appropriate.
Problem 7.6 Identify the nucleophile and leaving group and draw the products of each substitution reaction. + OCH,CH " . NAOH + NaOH - FL + N O . NACN + NaCN - Problem 77
For the following reaction, identify the nucleophile, electrophile, and leaving group. 0 + A Br AB Nucleophile (Select] Electrophile (Select] Leaving Group (Select] Consider the following molecules: Br Ver - H Which will react the fastest in an SN2 reaction? [Select] Which will react the fastest in an E2 reaction? (Select]
For the following SN2 reaction, draw the organic and inorganic products of the reaction, and identify the nucleophile, substrate, and leaving group. Include wedge/dash bonds and H on a stereocenter. Select the statement that properly identifies the nucleophile, substrate, and leaving group.
4. Considering the structure of the substrate, the nature of the nucleophile, and the solvent (written on the arrows), determine the type of mechanism (Snl or S2) for every reaction. Predict the products and draw the mechanism DMF + KN3 ОН + water H-CI а) b) ethanol Br acetone CH3CH20H KI Br d) Br DMSO DMSO Br + КCN KSCH2CH3
For the following SN2 reaction, draw the organic and inorganic products of the reaction, and identify the nucleophile, substrate, and leaving group.Select the statement that properly identifies the nucleophile, substrate, and leaving group.
For the following SN2 reaction, draw the organic and inorganic products of the reaction, and identify the nucleophile, substrate, and leaving group. Select the statement that properly identifies the nucleophile, substrate, and leaving group.
In the substitution reactions below, draw the major product in the box provided and indicate in the small box whether the reaction is SN1, SN2, or neither. Be sure to show all stereochemistry. If more than one enantiomer is produced, write "+Enant" in the box with the product. [10] Product SN1/SN2/Neither NaCN Br DMSO NaOEt EtOH Br NaOMe MeOH NaOH Expensive Acetonitrile CH,Br DMF Nat