Question

Indicate which reaction type is favored for each substrate (Questions 19-21) acidic 19. R,CX - solution Each term may be used more than once or not at all. a. E1 Nu b. Sn1 20. RCH,X c. E2 d. SN2 strong 21. R,CHX base Consider the pair of reactions below to answer the following (Questions 22-25) KI 1 + KBr Reaction des de Acetone Reaction A

Answer 1

Solution In this reaction the substrate is om tertiary alkyl holide so very much crowded. In acidic solution it readily endange dehologenetion to form ano a carbocotion which is tartiary so very much stable in acidic solution. Now in solation 14₃0 present which is a mudeophile so, to readily attack to the corrbocation to form a tertiary alchol. Therefore it is a Sut reaction. R₂cy acidic Raet H₂O Solution 30 -120 Rze-off stable alehol carbocetion u Itna SNL reaction. 26 R. CH2X Nu , Here the substrate in a primary alkyl helide. So in presence of nucleophile it undergo 32 reaction Amoothly. As the substrate in primary so SN2 fororred and in presome of ter bare nucleophile M 21 Route R-CH₂-X = cfx/ Nu No 17 H in It is a SN2 reaction

21) ROCHA Strony bone In this reation the substrate in secondary alkyl helide and reagent giren strong bese. When the basic strength of the reagent increases elimination reaction is likely to take place. Hore also elemination reaction eccure El or E2 As the substrate is secondry so, there might be reaction KI acetoré Here the substrate is a primary akkyl helide. And the recent giren kI which is a good nucleophile in the polar oprotic medium acetone. As the alkyl halide is primary celess hindered se, the I a r Ottack from the to the backsite of the substrate to tor and simultaneously Bro leares to form the following product. so, this a sua reation Mars