Write a synthetic scheme (start with benzene or toluene) for the preparation of the following. Assume...
2. Propose a syntheses of the following compound starting with benzene. Assume ortho and para isomers can be separated. (1 UN ONK , COOH COOH
Starting with benzene as your only source of aromatic compounds, how would you synthesize the following substances? Assume that you can separate ortho and para isomers if necessary. p-Chlorotoluene m-Bromonitrobenzene o-Bromobenzenesulfonic acid m-Chlorobenzenesulfonic acid Starting with either benzene, phenol, or toluene, how would you synthesize the following substances? Assume that ortho and para isomers can be separated 2-Bromo-4-methylphenol 1,3,5-Trinitrobenzene 2,4,6-Tribromoaniline 2-Chloro-4-nitrotoluene
Outline all steps in the laboratory synthesis of the following compounds from benzene and/or toluene, using any needed aliphatic or inorganic reagents. Assume the para isomer can be separated from an ortho,para mixture. Do not show mechanisms. p-bromobenzoic acid m-bromobenzoic acid 2-bromo-4-nitrotoluene 2-bromo-4-nitrobenzoic acid 4-bromo-3-nitrobenzoic acid o-iodobenzoic acid
Aromatic Synthesis Reactions Starting with benzene, propose syntheses to carry out each of the following conversions. Assume ortho and para isomers can be separated.
Outline a synthetic sequence for the following compound from methylbenzene. Assume the para isomer (not the ortho isomer) may be separated efficiently from any mixtures of ortho/para substitution products.
Write the structure of a major product when benzene reacts with neopentyl bromide (1-bromo-2, 2-dimethylpropane) in the presence of AlCl_3/heat Show the reaction mechanism of this reaction and name the product Using retrosynthetic analysis, devise a synthesis of 2-nitroterephthalic acid ft benzene by using any necessary organic and inorganic reagent (Assume that ortho and and para-isomers are easily separable in the laboratory.) Identify compounds A-C in the retrosynthesis shown below and suggest reagents for each synthetic stop.
Write out the retrosynthesis, forward synthetic steps, reactants, and intermediates for the following synthetic scheme. CH2CH3 O
Write out the retrosynthesis, forward synthetic steps, reactants, and intermediates for the following synthetic scheme. CH2CH3 O
The following flawed synthesis was given, and now it
is asking for an alternate synthetic scheme that will provide the
desired product from benzene.
1JO PU O I OCULU. (a) Write the proposed (flawed) synthesis you were given for WP question 6. (b) Propose an alternate synthetic scheme that will provide the desired product from benzene. We were unable to transcribe this image
17-52 Show how you would synthesize the following compounds, starting with benzene or toluene and any necessary acyclic reagents. Assume para is the major product (and separable from ortho) in ortho, para mixtures. 1-phenyl-1-bromobutane 1-phenyl-1-methoxybutane 3-phenylpropan-1-ol ethoxybenzene 1,2-dichloro-4-nitrobenzene 1-phenylpropan-2-ol p-aminobenzoic acid 2-methyl-1-phenylbutan-2-ol 5-chloro-2-methylaniline 3-nitro-4-bromobenzoic acid 3-nitro-5-bromobenzoic acid 4-butylphenol 2-(4-methylphenyl)butan-2-ol
Propose a syntheses to carry out the following conversion. Assume ortho and para isomers can be separated.