Outline all steps in the laboratory synthesis of the following compounds from benzene and/or toluene, using any needed aliphatic or inorganic reagents. Assume the para isomer can be separated from an ortho,para mixture. Do not show mechanisms.
p-bromobenzoic acid
m-bromobenzoic acid
2-bromo-4-nitrotoluene
2-bromo-4-nitrobenzoic acid
4-bromo-3-nitrobenzoic acid
o-iodobenzoic acid
Outline all steps in the laboratory synthesis of the following compounds from benzene and/or toluene, using...
Outline a synthesis of the following compound from benzene (C_6H_5), methane (CH_4) and any needed inorganic reagents. Assume that ortho- and para-substitution products can be separated.
17-52 Show how you would synthesize the following compounds, starting with benzene or toluene and any necessary acyclic reagents. Assume para is the major product (and separable from ortho) in ortho, para mixtures. 1-phenyl-1-bromobutane 1-phenyl-1-methoxybutane 3-phenylpropan-1-ol ethoxybenzene 1,2-dichloro-4-nitrobenzene 1-phenylpropan-2-ol p-aminobenzoic acid 2-methyl-1-phenylbutan-2-ol 5-chloro-2-methylaniline 3-nitro-4-bromobenzoic acid 3-nitro-5-bromobenzoic acid 4-butylphenol 2-(4-methylphenyl)butan-2-ol
Starting with benzene as your only source of aromatic compounds, how would you synthesize the following substances? Assume that you can separate ortho and para isomers if necessary. p-Chlorotoluene m-Bromonitrobenzene o-Bromobenzenesulfonic acid m-Chlorobenzenesulfonic acid Starting with either benzene, phenol, or toluene, how would you synthesize the following substances? Assume that ortho and para isomers can be separated 2-Bromo-4-methylphenol 1,3,5-Trinitrobenzene 2,4,6-Tribromoaniline 2-Chloro-4-nitrotoluene
Name: 4. Starting with benzene and any inorganic or organic reagents, outline all steps in the synthesis of the following compounds. No mechanisms required but correct order is. (HINT: think clectrophilic aromatic substitution) (10 points): (A) (B)
Starting with benzene or toluene, outline a synthesis of each of the following compounds using diazonium salts as intermediates a) 3,4,5-Tribromobenzonitrile b) 2,6-Dibromobenzoic acid
Outline the synthesis of the following compounds from the compound given. 4-nitro-2, 6-dibromoanisole from anisole. 4-bromo-2-nitrobenzoic acid from o-nitrotoluene. 2, 4, 6-tribrom from aniline. 5-nitroisophthalic acid from m-xylene 4-nitroisophthalic acid from m-xylene
Name: 4. Starting with benzene and any inorganic or organic reagents, outline all steps in the synthesis of the following compounds. No mechanisms required but correct order is. (HINT: think clectrophilic aromatic substitution) (10 points): (A) (B)
outline labratory syntheses of each of the following compounds starting with benzene and any other reagents Outline laboratory syntheses of each of the following compounds, starting with benzene and any other reagents. (c) CI (a) p-nitrotoluene (b) p-dibromobenzene (c) p-chloroacetophenone (d) m-nitrobenzenesulfonic acid (e) p-chloronitrobenzene (f) 1,3,5-trinitrobenzene (g) 2,6-dibromo-4-nitrotoluene
Outline a feasible laboratory synthesis of m-bromoethylbenzene, starting with benzene, using any available reagents, compounds, etc.
Write the structure of a major product when benzene reacts with neopentyl bromide (1-bromo-2, 2-dimethylpropane) in the presence of AlCl_3/heat Show the reaction mechanism of this reaction and name the product Using retrosynthetic analysis, devise a synthesis of 2-nitroterephthalic acid ft benzene by using any necessary organic and inorganic reagent (Assume that ortho and and para-isomers are easily separable in the laboratory.) Identify compounds A-C in the retrosynthesis shown below and suggest reagents for each synthetic stop.