Folic acid, shown below, is used to treat anemia and as a supplement during pregnancy. How...
Question 5 (1 point Why is taking a folic acid supplement especially important during pregnancy? To reduce the risk of developing multiple sclerosis To reduce the risk of pre-eclampsia To reduce the risk of neural tube defects (NTDs) To reduce the risk of low birth weight
Methyldopa (C10H13N04) is used to treat high blood pressure during pregnancy. Its molecular structure is shown below. The pka of the carboxylic group is 1.7 and the pk of the amine group is 4.2. Which of the following forms of this drug is likely to be present in our blood which has a pH close to 7.4? НО. ОН NH2 НО НО. он NH2 NH НО НО с. Но d. HO он NH2 HO НО o А а.
2. Folic acid is a molecule needed in the synthesis of nucleotides. Many bacteria have an enzyme that can bind the molecule, PABA, and catalyze its conversion into folic acid. Bacteria that cannot make folic acid will die. Sulfanilamide is an antibiotic used to treat certain bacterial infections by killing the bacterial cells. Examine the molecular structures below and propose a likely mechanism for the function of sulfanilamide. (4pts) HO, O O=S=0 NH2 NH2 NH2 Sulfanilamide DARA cataluzer
Loratadine, shown below, is an antihistamine commonly used to treat allergy symptoms. What is the hybridization of the atom labelled B? This atom is not hybridized. | OOO
Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat meningitis, pneumonia, sepsis. and urinary tract infections. Its structure is shown below. How many stereogenic chiral carbon centers do we have in the structure of Polymyxin B? Select one: a. 13 O b. 15 O c.ll 0 d. 14 f10 9.8 h. 12
4. Answer questions based on the following structure: (17 marks) a) Name the functional groups that are circled in the structure below (6 marks) b) Answer questions based on the above structure: • Give the hybridization for the atoms (11 marks) Give approximate bond angles about the atoms labeled: CF: • How many C-Cx bonds are there? How many pairs of lone pair electrons are there? • What is the total number of sp2 hybridized carbon atoms? • What is...
Question 6 1 pts Loratadine, shown below, is an antihistamine commonly used to treat allergy symptoms. B ci What is the hybridization of the atom labelled D? This atom is not hybridized. sp
Q6 1 Point How many spể hybridized carbon atoms are there for the following organic molecule? ОН О 12 o 14 ооо 15 o 13
Q6 1 Point How many spể hybridized carbon atoms are there for the following organic molecule? ОН О 12 o 14 ооо 15 o 13
Consider the molecule shown below, and the pair of energy diagrams, for the next set of questions. Enter the letters corresponding to atoms in the molecule (abc etc). If none of the atoms apply, input none 1. Which of the atom(s) is/are sp3 hybridized? Molecules with sp? hybridization have 4 σ bonds (C) or 3 σ bonds and a lone pair (N) or 2 σ bonds and 2 lone pairs (O). Enter none, if none of the atoms have this...