Reaction I is the first committed step in fatty acid synthesis, and reaction II is the first step in the conversion of pyruvate to glucose in gluconeogenesis. Both acetyl-CoA and pyruvate are carboxylated at the expense of ATP. What is the chemical logic behind this energy expenditure in both cases? For full marks, provide your answer with reaction schemes and electron pushing arrows.
Reaction I is the first committed step in fatty acid synthesis, and reaction II is the...
In the first step of fatty acid synthesis, _a___ is carboxylated. The carboxyl group is then transferred to _b_, which becomes _C_ Oa) acetyl coA, b) biotin, c) malonyl coA a) biotin, b) acetyl coA, c) malonyl coA a) malonyl coA, b) biotin, c) acetyl coA
Need help with both questions, thank you! Question 13 The committed step of fatty acid synthesis is catalyzed by the enzyme acetyl CoA carboxylase. Which of the following accurately describes this enzyme? None of the choices is correct. All of the choices are correct Phosphorylation of the enzyme inhibits its activity. The inhibited enzyme can be stimulated by allosteric regulation of citrate. The dephosphorylated enzyme is active. Question 14 Formation of this molecule is the committed step of fatty acid...
The synthesis of ____________ is the first committed step of fatty acid synthesis and the enzyme that catalyzes this reaction,_____________ is the major site of regulation of fatty acid synthesis.
HMG CoA Reductase Catalyzes the first committed step in fatty acid synthesis True or false
9. a. Describe the various ways that Acetyl-CoA Carboxylase, the first committed step of fatty acid biosynthesis, is regulated. b. Predict whether this enzyme is likely to be active in the fed state or the fasted state, and provide a rationale for how this activation occurs given your answer to part a.
Fatty Acid Metabolism. The reactions of the fatty acid spiral are shown below. Use the description on the left side of the page to classify the reactions and fill in the boxes on the right side of the page Activation Step. The activation of the fatty acid begins by the addition of CoA which will carry the fatty acid from the cytosol into the mitochondria. The product, which is a fatty acid with a CoA attached, is known as a...
2) Use this intermediate in fatty acid synthesis ACP The synthesis of this intermediate required one molecule of malonyl CoA two molecules of malony CoA three molecules of malonyl COA four molecules of malony CoA five molecules of malonyl COA Not listed 7) The molecules shown below are intermediates found in one round of fatty acid synthesis after the condensation step. so ACP ACP Which round of fatty acid synthesis is occurring in the reactions shown? The intermediate above is...
8. Draw the overall coupled reaction showing the conversion of pyruvate into acetyl CoA. dono STEP 2 nach do not ww what are true. Ir raise, change one word in the statement so that it is true. a. The pyruvate produced from glycolysis must be consumed in some way or glycolysis stops. b. Glycolysis produces ATP directly. too C. Glycolysis breaks down glucose into acetyl CoA. d. Glycolysis is aerobic
In the first step of fatty acid oxidation, the fatty acid (R-COOH) is converted to its coenzyme A derivative in the following reaction: R-COOH + ATP + COA-SH -->R-CO-S-COA+AMP+PP The standard free-energy change (Delta G") for this reaction is -15 kJ/mol. Another reaction drives the reaction forward to a greater extent. This reaction is: A. Pyrophosphate is hydrolyzed to 2 phosphate molecules B. AMP is hydrolyzed to adenine C. The fatty CoA precipitates to remove it from the product side...
Please help and explain answers! 1. In a series of chemical reactions, glucose is first converted into __________. a) pyruvate b) glycerol c) acetyl CoA 2. In the process of glycose breaking down, hydrogen and electrons are carried by coenzymes made from the ___. a) B vitamin biotin b) B vitamin niacin c) vitamin thiamine 3. In the Cori Cycle, the conversion of lactate to glycose by anaerobic glycolysis in the muscle requires energy from ___________. a) acetyl CoA b)...