(A) is Glucose (which is starting material for glycolysis)
(B) is Hexokinase enzyme (which convert glucose into glucose-6-phosphate)
(C) is glucose-6-phosphate (in which phosphate group is attached at 6th position)
(D) is phosphoglucose isomerase (which converts glucose-6-phosphate to fructose-6-phosphate).
(E) is fructose - 6-phosphate (having carbonyl group at 2nd carbon)
(F) is fructose-1,6biphosphate (formed by fructose-6-phosphate by the enzyme phosphofructokinase)
(G) is dihydroxy acetone phosphate (in which carbonyl group is in the middle).
(H) is glyceraldehyde-3-phosphate (having aldehyde group).
1. Fill in the glycolysis diagram with the names of the missing intermediates and enzymes. Then...
CHOPO 1. Fill in the glycolysis diagram with the names of the missing intermediates and enzymes. Then use the diagram to answer the questions. OOP Glu CLORO $ H-C-OH HC-OH Phosphoghoeroms HÀ -H 000 H-C-OH H-O-OH H-C-OPO -0--PO CH OH KM HO CLOU CO 100-C-H -C-O11 H-C-OH CORO Phosphort CH-0--PO, C= o 100-C-1 | 011 H-C-OH cho- -0- 0- CEO CHLOHN | 110
2a Which reactions require ATP? Which reactions produce ATP? What is the net yield of ATP for every mole of glucose that enters the glycolysis pathway? 2b What are AG' and AG' for the glycolysis pathway? Is this pathway catabolic or anabolic? 2c Which step is an illustration of a reverse aldol condensation? 2d. Define substrate level phosphorylation. Which of these compounds in the glycolysis pathway have a large phosphate group transfer potential? 2e. Which steps are examples of redox...
1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and intermediates and draw the glycolytic pathway. Decorate the diagram by adding ATP, ADP, H", NADH, NAD', P, and H20 where necessary. All the steps are reversible except 1, 3 and 10; draw appropriate arrow. First arrange the reactants in the correct order. Reactants/intermediates: 3-phosphoglycerate glucose Phosphoenolpyruvate dihydroxyacetone phosphate Pyruvate glucose 6-phosphate 1,3-bisphosphoglycerate fructose 6-phosophate 2-phosphoglycerate glyceraldehyde 3-phosphate fructose 1,6-bisphosphate Enzymes: Phosphoglucoisomerase phosphoglycerate kinase phosphoglycerate...
25. Fill the blanks with the names of reactants/products and enzymes in the glycolysis (Please note the unit for AG" is kcal/mol (1kcal/mol = 4.1868 kJ/mol). CH,OPO Јcн,ОРО CH,OH да" -4.0 н н дG". +0.4 T os AGE-34 ATP ADP OH на неон нон Он н снуOPO . CH,OPO не но он он уон Он н G +5.7 AG= +1.5 с-от 4c-o сн,ОРО HCOPO c-o нсон Сн,OPO с-ОРОЗ нсон сн,ОРОР Знсон 2c-o AG"=+1.1 CHOW ATP ADP NAD CHOPO AC 18...
1. Fill in the missing reagents for each reaction in the following spider diagram: SOH 2. Fill in the missing product(s). Cl2 FeCl3 AICI CHO HNO3, H2SO4 HNO3, H,SO4 3. Propose a synthesis for the following transformation. COOH 0-6 NO2
1. Give stepwise mechanisms for the following reactions. Clearly show all intermediates and use arrows to show electron movement. - Hop Wow Peonic plure H-Br RO-OR, heat I Br b. R oh solla Red + S02 + Hl- c. Al cu. -CH = CH –O-CH3 Hbg, 4pH OH + HCl. 0 KOEI 1. Nat o Et, Etoh il I 10, EL + C CH₂ OH 2. Hoot TOE 1.HCl, H₂O 2. Et3N, Eto ce U
Glycolysis activity 1: Metabolic pathway puzzle Try to complete the activity without using the textbook. 1. Slides 4 and 5 show the 10 reactions for glycolysis, but some of the molecules are missing. Draw the missing molecules in the proper place (on the handout). The missing molecules are shown on the next slide, you have to use the clues on the handout and your organic chemistry knowledge to figure out where each molecule belongs. 3. In the red dotted boxes...
missing reagents, please explain
9. (20) For each of the following reactions, fill in the missing reagents for the formation of the product shown. Sequential steps. numbered. Reagent List: reagents from the list provided s necessary, should be HyC-Br Nah NaOH H,C- CH ( MCI) HBECH,OH Br-Br O=C=0 HOÀc) (LDA) 041 H2o depromat ΝΛΗ noad to Nattpostele Br Br-Brz H3C H-BK H4C1-NH2 H3C H,C CH, Br H2C+NCHE HEC CH2 LOA B
. Fill in the missing reactant(s) and/or product(s) [32 points total 2 points each) 1. CH2MgBr (excess) CH CH2CH H H-C-H excess heat H20 F. NH-NH2 CH3CH2OH G. он OCH2CH3 H2CHs H. o O 1. NaOCH2CHs 3. H30 OCH2CHs 2. CH,Br 4. heat
12. What does the word 'antagonist' mean in the pharmaceutical world? 13. Fill in the missing information: of an old -NH2 [H'] NaNO2 HCI NaBH,CN NH2 1. Excess CH31 2. Ag,0,H,O, heat 3. Bry, Ca, NO2 Н.С. CH Multiple Steps G= CH