4) What carbonyl compound and Grignard reagent could be used to prepare 2- butanol? CHÚCHO CHỊCH,MgB...
What Grignard reagent and what carbonyl compound might
you start with to prepare the following alcohols?
(a)
(b)
(c)
(d)
(e)
(f)
3. What Grignard reagent and what carbonyl compound might you start with to prepare the following alcohols? OH CH3CHCH2CH3 CH3CH2CHCH2CH HC CH2OH OH
III. Grignard Reagents. 1. (6 pts) Provide two different syntheses for 1,1-diphenyl-1-butanol starting from a carbonyl compound and using a Grignard reagent. Synthetic Route 1: carbonyl Grignard reagent a) THE b) H3O+ work up OH 1,1-diphenyl-1-butanol Synthetic Route 2: carbonyl Grignard reagent a) THE b) H3O+ work up 1,1-diphenyl-1-butanol
What Grignard reagent and what carbonyl compound might you start with to prepare the following alcohol? но сна -CH₃ • Draw the Grignard reagent as a covalent magnesium bromide. • Any ester used should be a methyl ester. • If there is more than one combination, draw only one. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate multiple reactants using the + sign from the drop- down menu....
Give three different sets of reagents (a carbonyl compound and a Grignard reagent) that could be used to prepare the following compound. OH CH3-C-CH2CH3 CH3 Check all that apply Check all that apply. CH3 CH2 COCHg and CH3 MgBr CH, CH2 COCH3 and 2CH3 MgBr CH3 CH2 C CH3 and CH3 MgBr CH3 C CH3 and CH3CH, MgBr 0 CH3 C OCHZ and CH3CH, MgBr CH3CH, C CH3 and 2CH3 MgBr Submit Previous Answers Request Answer
Which combination(s) of alkyl bromide and carbonyl compound can be used to prepare the following product by addition of the Grignard reagent derived from the alkyl bromide to the carbonyl compound? OH CH3BT CH3CH2CH2Br CH3CH2BT (CH3)2CHBO OA. only 3 and 4 only 2 and 3 OC.only 1, 2 and 3 OD.only 1 and 2
#6 Which combination(s) of organic bromide and carbonyl compound can be used to prepare the alcohol in the box by reaction of the Grignard reagent derived from the alkyl bromide with the carbonyl compound? Wrong Answer B OCH CH3Br CH3Br 3 a) only 1 b) only 1 and 2 c) 1, 2 and 3 d) only 3 and 4 e) 1,2,and 4
#6 Which combination(s) of organic bromide and carbonyl compound can be used to prepare the alcohol in the box by reaction of the Grignard reagent derived from the alkyl bromide with the carbonyl compound? Wrong Answer B OCH OCH CH3Br CH3BT OH a) only 1 b) only 1 and 2 c) 1, 2 and 3 d) only 3 and 4 e) 1,2,and 4
8. Give the Grignard and Carbonyl compound needed to make each of alcohols. (6 points, 2 each) nd needed to make each of the following you - 9. Circle the compounds that could not be made into a Grignard Reagent. Br 10. Show how you could convert the compound below into a Grignard reagent without having it destroy itself. (4 points)
1. (6 pts) Provide two different syntheses for 1,1-diphenyl-1-butanol starting from a carbonyl compound and using a Grignard reagent. Synthetic Route 1: carbonyl Grignard reagent a) THE b) H30* work up 1,1-diphenyl-1-butanol Synthetic Route 2: carbonyl Grignard reagent a) THF b) H30* work up ОН 1.1-diphenyl-1-butanol 2. (3 pts) The use of Grignard reagents requires scrupulously dry aprotic solvents such as diethyl ether or tetrahydrofuran. Please explain why the solvents need to be scrupulously dry. To support your reason, show...
Problem 1. Synthesize the following alkene through the Wittig reaction of a carbonyl compound and a Wittig reagent. 2,3-diphenyl-2-butene 2. Predict the products of the following reactions. Casco CHCH.CHCH, CHCH.CH но ats ОО 2.0 CH,CHACHCH,CHCHOCH.CH, CH 3. A useful and general method for the synthesis of alcohols is the addition of Grignard reagents to carbonyl compounds. Show what Grignard reagent and what carbonyl compound you would start with to prepare the alcohol below. List all possibilities. 2-methyl--butanol 2-METHYL-2- BOTANIC