What Grignard reagent and what carbonyl compound might
you start with to prepare the following alcohols?
(a)
(b)
(c)
(d)
(e)
(f)
What Grignard reagent and what carbonyl compound might you start with to prepare the following alcohols?...
What Grignard reagent and what carbonyl compound might you start with to prepare the following alcohol? но сна -CH₃ • Draw the Grignard reagent as a covalent magnesium bromide. • Any ester used should be a methyl ester. • If there is more than one combination, draw only one. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate multiple reactants using the + sign from the drop- down menu....
8. Give the Grignard and Carbonyl compound needed to make each of alcohols. (6 points, 2 each) nd needed to make each of the following you - 9. Circle the compounds that could not be made into a Grignard Reagent. Br 10. Show how you could convert the compound below into a Grignard reagent without having it destroy itself. (4 points)
Problem 1. Synthesize the following alkene through the Wittig reaction of a carbonyl compound and a Wittig reagent. 2,3-diphenyl-2-butene 2. Predict the products of the following reactions. Casco CHCH.CHCH, CHCH.CH но ats ОО 2.0 CH,CHACHCH,CHCHOCH.CH, CH 3. A useful and general method for the synthesis of alcohols is the addition of Grignard reagents to carbonyl compounds. Show what Grignard reagent and what carbonyl compound you would start with to prepare the alcohol below. List all possibilities. 2-methyl--butanol 2-METHYL-2- BOTANIC
Show how you would use Grignard syntheses to prepare the following alcohols from the indicated starting materials and any other necessary reagents. Draw the Grignard reagent and any other organic reagents needed. 11 RUVIUWI Constans i Pendulu Part F Show how you would use Grignard syntheses to prepare the following alcohols from the indicated starting materials and any other necessary reagents. Draw the Grignard reagent and any other organic reagents needed. ОН -C-CH CH, from C-OCH.CH Draw the molecules on...
4) What carbonyl compound and Grignard reagent could be used to prepare 2- butanol? CHÚCHO CHỊCH,MgB CHÚCH3CHO CHUMBA CHÚCOCH CHUMB UU I Only! Only II Only III Only Land
7. Circle the compounds that could be successfully react with a Grignard reagent as substrates in a Grignard synthesis. (5 points) 에 HC) O CH₂ H₃CC-CH3 8. Give the Grignard reagent and carbonyl compound need to make each of the following alcohols. (6 points, 2 each) 9. Circle the compound that would be most acidic (have the lowest pKa, highest Ka) (5 points)
Give three different sets of reagents (a carbonyl compound and a Grignard reagent) that could be used to prepare the following compound. OH CH3-C-CH2CH3 CH3 Check all that apply Check all that apply. CH3 CH2 COCHg and CH3 MgBr CH, CH2 COCH3 and 2CH3 MgBr CH3 CH2 C CH3 and CH3 MgBr CH3 C CH3 and CH3CH, MgBr 0 CH3 C OCHZ and CH3CH, MgBr CH3CH, C CH3 and 2CH3 MgBr Submit Previous Answers Request Answer
#6 Which combination(s) of organic bromide and carbonyl compound can be used to prepare the alcohol in the box by reaction of the Grignard reagent derived from the alkyl bromide with the carbonyl compound? Wrong Answer B OCH OCH CH3Br CH3BT OH a) only 1 b) only 1 and 2 c) 1, 2 and 3 d) only 3 and 4 e) 1,2,and 4
II. What carbonyl compounds and Grignard reagents would you use to make the alcohols shown below? Show all possibilities. No mechanism necessary. (8 pts) НО. b OH
Which combination(s) of alkyl bromide and carbonyl compound can be used to prepare the following product by addition of the Grignard reagent derived from the alkyl bromide to the carbonyl compound? OH CH3BT CH3CH2CH2Br CH3CH2BT (CH3)2CHBO OA. only 3 and 4 only 2 and 3 OC.only 1, 2 and 3 OD.only 1 and 2