Question

30. a) Complete the figure below by naming each labeled item or process. Include an appropriate legend for the figure which summarizes the illustration. Explain in a short paragraph (3-4 sentences) the mechanism of antigen processing and presentation shown here. (3 points) Viral proteins & 1h Cross-presenta sentation? Nucleus Legend ?

Answer 1

This the process of "Professional antigen-presenting cells process intracellular and extracellular pathogens."

A represnts - Exogenous pathway

B represnts - Endogenous pathway

C represnts - Extracellular pathogen

D represnts - Phagosome

E represnts - Entigen representaion to helper cells

F represnts - Virus

G represnts - Cytolplasm

H represnts - Endiplasmic reticulum

I represnts - Antigen presentation to CTLs (Cytotoxic T-lymphocytes)

ligands - T-cells and CTLs

MECHANISM OF ANTIGEN PROCESSING- The usual process of antigen presentation through the MHC I molecule is based on an interaction between the T-cell receptor and a peptide bound to the MHC class I molecule. There is also an interaction between the CD8+ molecule on the surface of the T cell and non-peptide binding regions on the MHC class I molecule, here some proteosome degradation is also involved.