Ans: In some of the cases, the of the dominant pathogenic mutations for the cell or the organism may be too critical for the mutation to be transmitted to new born offspring. Heterozygous mutations of FGFR3 gene cause thanatophoric dysplasia, which is a serious bone disorder. New born offspring become affected and die at birth because they are unable to breathe.One more serious mutation are specific activating mutations in the G protein-coupled receptor encoded by GNAS complex locus (GNAS). The lithality rate is huge for dominant pathogenic mutations so the segregation frequency is lasser than the recessive pathogenic mutation.
Question 2: Explain why recessive pathogenic mutations often segregate at higher frequencies than dominant pathogenic mutations...
Explain why recessive pathogenic mutations often segregate at higher frequencies than dominant pathogenic mutations in human populations. (3 points)
Question 3: Explain why recessive lethal alleles often segregate at lower frequencies in dog populations than in wolf populations. Hint: Dogs are inbreeding populations. (3 points)
Question 3: Explain why the fixation time of a beneficial, recessive allele is often much longer than that of a beneficial, dominant allele. (2 points) Question 4: Name two types of natural selection that can maintain polymorphism. (2 points) Question 5: Consider an annual plant population in an environment with alternating dry and wet years. You observe the dry and wet years are equally frequent. At a locus with two alleles (A1 and A2), the relative fitnesses of the three...
2. (4pts) In a strain of Petunia that normally have purple flowers, recessive and dominant mutations at the red color locus (R locus : R+ = wildtype allele, purple) lead to different flower colors. Plants that carry a particular dominant allele Ra have pink petals. Of the individuals that carry one allele of the dominant allele Rb roughly 20% have normally colored purple petals, the remaining 80% show a range of lighter red colors. Individuals that are homozygous for Rb...
Cor.. 38 wor D Question 10 2 p Do dominant alleles have a higher fitness (better survival rate) than recessive alleles? Why or why not?
Is this a dominant or recessive trait? Explain why. What are the genotypes of l-1 and l-2? What is the chance of the next child of individuals lll-5 and lll-6 is affected? (More Challenging) IV-1 marries someone with the trait, what is the chance of their child being affected?
Can you explain how to do number 4? dominant individual and umail mmetance, hów can one differentiaté between a homozygous one who is heterozygous for the dominant trait? (A) By crossing the individuals in question (B) By crossing each individual with a known homozygous recessive and examining the offspring By crossing each individual with a known heterozygote and examining the offspring (C) (D Both B and C If a male hemophiliac (Xhy) is crossed with a female carrier of both...
1. Based on your understanding of sex-linked recessive traits, would it be possible for the phenotype to skip one or more generations before reappearing? Explain your answer. 2. Proteomics is the study of the number of different proteins that a gene produces. Why might this be a more complete snapshot of human genetics than genomics? 3. If the Huntington’s disease trait is dominant, why is it not more prevalent in the population?
2. Hardy-Weinberg Equilibrium; chi-square test Sickle cell anemia is a recessive disorder caused by a recessive mutation (S) in the b-hemoglobin gene. 80% of affected SS individuals die before reproducing. Heterozygotes (AS) and homozygous dominant (AA) individuals do not have sickle cell anemia. The table below shows the number of people of each genotype in a population of 100 people in population of Cameroon. Observed # individuals in a Cameroon population AA AS SS 62 32 6 What are the...
Heterozygous, dominant Heterozygous, recessive QUESTION 2 In the Star Trek universe, Tibbles are small furry creatures with a penchant for reproduction You are studying three genetic loci aff determines the fur length, gene B determines the fur color, and gene C determines it has both male and tomale sex organs), you have found conditions amenable to frequencies for gones L, B and C Land B 5% Land C 32% B and C 30% whether the fur is straight or curly...