Question

In the schematic, the position of a two turn RSS (dark triangle) is shown. Below the schematic, I provide a key to various DNA sequence motifs (labeled A-E). In the answer box, indicate the appropriate DNA motif (using the key) for each 5' and 3' location that would immediately flank (contact) each of the 7 gene segments that is required for VDJ re-arrangment. This means that you will have a total of 14 answers and that answers can be used more than once. Assume that all gene segments are oriented in the same direction. A = 2 turn RSS B = Switch Region C = no RSS D = Both 1 turn and 2 turn RSS E = 1 turn RSS

Answer 1

日→ A A . E A E A E