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TFIIB contributes to pre-initiation complex formation by O A. Enhancing TFIID binding to DNA. Positioning the catalytic site
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Answer #1

Answer: "E" - A, B and C are all correct

Explanation: TFIIB is added to the preinitiation complex in a sequential manner after the recruitment of TFIID or TBP(TATA box Binding Protein), and the recruitment of TFIIB stabilizes the TFIIB-TFIID-DNA complex.

Thus the statement "A" is correct

Statement "B" is also correct. With the help of other factors, the TFIIB complex helps to recruit the RNA pol to the transcription start site(+1 site).

Statement "C" is also correct, the TFIIB interacts with TBP through its C-terminal domain.

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