Question

Strong-binding YO Transition from weak- to strong-binding Weak-binding 20 40 60 80 Po, (mm Hg) 100 120 Analyze the binding curve by completing the following sentences. Match the words in the left column to the appropriate blanks in the sentences on the right. View Available Hints) Reset Help decrease Of the two axes in the oxygen binding curve, the y-axis shows the increase where the percentage of bound and unbound oxygen binding sites can be determined. An axis value of 0.4 means that 40% of hemoglobin oxygen binding resting tissues weak sites are to oxygen within the sample (ex. blood sample) Conversely, this also signifies that 60% of those available oxygen binding sites are strong to oxygen. concentration of hemoglobin in the system The x-axis identifies the as a partial pressure. Different locations within the human body correspond to varying partial pressures of oxygen. A value of -100 mm Hg is the oxygen concentration in the and a value bound of 30 mm Hg is the oxygen concentration in the lungs The hemoglobin curve is sigmoidal and illustrates the changing oxygen binding fraction of hemoglobin binding sites bound to 02 affinities of hemoglobin. Without oxygen bound, hemoglobin is in a -binding state that impacts the binding of the first oxygen. The first not bound oxygen that binds to hemoglobin binds independently of the other subunits (non- concentration of oxygen in the system cooperatively). After the first oxygen binds, the structure of the subunit changes, consequently changing the structures of the other hemoglobin subunits. These structural changes the affinity of hemoglobin for binding oxygen. Submit

Answer 1

1st box:- 1. Fractional saturation of the protein.

2. Bound

3. Not-bound

2nd box:- 1. concentration of oxygen in the system

2. lungs

3. resting tissues.

3rd box:- 1. weak

2. increases

these options are correct present in left column. remaining options are given to confuse you.