January 2019 December 2018 Wednesday (Infectious disease) G Be able to contrast the types of of microbe-human interaction. pathogers and levels Different types of pathogens are given below -- Fungi, Protozoa, Parasitic worms, viruses (Enveloped, Non enveloped), Helminth, prions, Mycobacteria, spores of bacteria (gram tve & gram -ve both), viroid, Animals are serve as vector, that carmy pathogenes from one host to another host. Losquitoes, tichs, flies etc. Microbe - human interaction - Mainly three types of micro-organisms are associated with human body Thursday (1) Normal microbiota. Microbes colonizes the heman body caithra hamming it. (10Transient microbiota - Rapidly lost from body{ skin surface) . pathogenic microbiota - It invade and damage the immune eaus. tissues etc. 2020-3-10
21 (2) Be able to differentiate the neop of pathogenin and virulence Pathogenicity It is ability of microbes to caus infection. The ability represents the genetic comporen of the pathogen. Vipulence The degree of pathogenicity to which microber can invade and damage host tissues. virulence Often used interchangeably with pathogeniet; (3). Be able to oliscum the general proceso of bacterial infection diseases - Facure Entry - Adherence + Invasion + Calorization + gasthe-toxicity or 0 Saturday Invasive ne osetissuer damage disease .ext... 2020-3-10 1 Infection begins when an organism successfully entens into the body ground and multiplies, this is called colonization. Entry of pathogen takes place through mucosa, oral canities, nose eyes, anus or thraugs open wound. for bacteria adhesion is a preliminary procen to calonization and then penetration through tissues. Adhesion involves surface interaction between specific pecepter on cell membrane and liganar on the w bacterial serface Invasion is penetration of hoat cousand tissues 5 by a complex molecule called invasins, that target hest cells recoptons.
January 2019 December 2018 Sunday 9 surviving from host difense mechanism by producem several tosin that kills phagocytes. They produce capsule by which they can surnine inside the phagocyte. They produces several virulence factons, liklexoen 27 nds (fibrinogen coagulating coagulares, qeinases etc) and several tosions ceratosin, endotoxin etc for tinnue damage of host The dis changed microorganismes are the source of a new infection. They discharge from respiratory on Salivary postais, urogenital tract blood etc