Question

Match each immune system protein with its function or description. (Use each description once).

Toll-like receptor	Signaling molecule that causes vasodilation and increased permeability of blood vessels in an infected area Enzyme that helps to degrade bacterial cell walls; found in tears, saliva, and mucus Pattern recognition receptor that detects a broad class of foreign molecules Protein that presents fragments of intracellular pathogens on the cell surface Antibody that is most commonly involved in allergies Local signaling molecules that attract phagocytes to areas of injury or infection Protein that presents fragments of extracellular pathogens on the cell surface The most abundant type of antibody circulating in the blood and interstitial fluid Pentameric antibody that is particularly effective in agglutination of pathogens
Lysozyme
Class 1 MHC protein
Class 2 MHC protein
Chemokine
Immunoglobulin E (IgE)
Immunoglobulin G (IgG)
Immunoglobulin M (IgM)
Histamine

Answer 1

Toll like receptor	Pattern recognition receptor that detects a broad class of foreign molecules
Lysozyme	Enzyme that helps to degrade bacterial cell walls; found in tears, saliva, and mucus
Class 1 MHC protein	Protein that presents fragments of intracellular pathogens on the cell surface
Class 2 MHC protein	Protein that presents fragments of extracellular pathogens on the cell surface
Chemokine	Local signaling molecules that attract phagocytes to areas of injury or infection
Immunoglobulin E ( IgE)	Antibody that is most commonly involved in allergies
Immunoglobulin G ( IgG)	The most abundant type of antibody circulating in the blood and interstitial fluid
Immunoglobulin M ( IgM)	Pentameric antibody that is particularly effective in agglutination of pathogens
Histamine	Signaling molecule that causes vasodilation and increased permeability of blood vessels in an infected area

Toll like receptor:

Many molecules involved in innate immunity have the capacity of pattern recognition which means they have the capability to recognize a given class of molecules. Molecules with pattern recognition ability may be soluble ( Lysozyme) or may be cell associated receptors ( Toll like receptors).

Lysozyme:

It is a hydrolytic enzyme found in tears and mucus secretion. These enzymes can cleave the peptidoglycan layer of bacterial cell wall.

Class I MHC protein:

These glycoproteins are present in nearly all nucleated cells. Cytotoxic T ( T_c) cells generally recognize the antigen combined with Class I MHC molecules.

Class 2 MHC protein:

These glycoproteins are only present on antigen presenting cells such as macrophages, dendritic cell etc. Helper T cells ( T_H)generally recognize the antigen combined with Class 2 MHC molecules.

Chemokine:

Cytokines are secreted by the white blood cells and other cells in response to stimuli. Cytokines play an important role in regulating the development and behavior of immune cells. Chemokines belongs to the group of cytokines. They act as an chemoattractant.

Immunoglobuln: These are proteins with antibody activity.

Histamine: Histamine causes the widening of blood vessels ( Vasodilation) and it enhances the vascular permeability of blood vessel so that phagocytes and other immune cells can easily enter to the infected site.