Question

0.5. What fraction of the offsprings of two parents with Sickle cell trait would you expect to have Sickle cell anemia? Q.6.

Q.3. In the two protein gel electrophoresis labs done in this class, proteins were separated based on their net charge or the

Q.1. Fill the blanks in the table below by converting the values provided? ---milliliter 125 microliter - nanoliter ----milli

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0.6. In the diagram below, lanel represents electrophoretic pattern of standard proteins while lane 2, 3, 4 and 5 represent u

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Answer #1

Q5.

  • Sickle cell diseases or sickle cell anemia are genetic disorders of blood, or RBC, or are hemoglobinopathies.
  • Sickling of cells refers to the changing of normal shape of RBC to sickle like shape, due to polymerization.

Representation:

Normal: Dominant trait

  • Homozygous genotype = SS

Sickle cell trait

  • Heterozygous genotype =Ss

Sickle cell disease: Recessive trait

  • Homozygous genotype = ss
  • Genotype of parents Ss
  • Cross = Ss x Ss

Ss x Ss

S

s

S

SS

Ss

s

Ss

ss

PRobabiliy with sickle cell disease = 1/4

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