Question

1. Wallerian Degeneration A) describes what happens to the axon when there is myelinopathy B) is a specific disease C) rarely occurs in response to traumatic injury to the axon D) None of the above 2. Explain in 3 sentences or less what is the difference between regeneration and denervation. 3. Explain in 2 sentences or less how a muscle fiber that lost its connection to a motor neuron could regain a connection to a motor neuron.

Answer 1

Answer

Ans-1) C) rarely occurs in response to the traumatic injury to the axon

Explanation :- wallarian degeneration - results from axonal lesions and neuronal cell death.

It is a rare disease occurs due to traumatic lesions in neuron or any injury that causes cut to the neuron fibre.

It involves disruption of the myelin and axons along the entire length of nerve fibre distal to the cut/injury.

Ans-2) Regeneration is the re-growth of part of affected organs remaining tissue whereas denervation is a loss of nerve supply regardless of the cause.

Regeneration restore the nerve supply whereas denervation don't.

Ans-3) connection between motor neuron and muscle fibres can be restored when denervated fibres may be reinnervated by axonal sprouting.

Extra points:-

each muscle fibres are connected to the motor neuron through neuromuscular junction.

Connection between motor neuron and muscle fibre is lost by denervation which occurs as a result of injury or any disorders to the neuron.