Question

Partial Question 6 1.5/3 pts What are all the reasons why ketone bodies are produced in the body? To regenerate COA To increase gluconeogenesis So the liver can burn fats safely Rectangul For energy for the brain and other tissues

Answer 1

1- The correct options are

a- to regenerate CoA

b- to increase gluconeogenesis

d-for energy for the brain and other tissues

reason- Ketones and ketoacids are alternative fuels for the body that are made when glucose is in short supply. They are made in the liver from the breakdown of fats. Ketones are formed when there is not enough sugar or glucose to supply the body's fuel needs. This occurs overnight, and during dieting or fasting.  Ketone bodies are produced by the liver under the circumstances listed above, resultant of intense gluconeogenesis, which is the production of glucose from non-carbohydrate sources (including fatty acids). ketone bodies are also used to make acetyl-CoA into long-chain fatty acids.

2- The first enzyme involved in ketogenesis or ketone body formation is Thiolase which converts 2 molecules of Acetyl-CoA into one molecule of Acetoacetyl-CoA.

Whereas HMG-CoA lyase enzyme converts HMG-CoA into Acetoacetate , which is the third step of ketogenesis