Question

Draw the structures of the following coenzyme molecules: 1. COA-SH/Acetyl-S-COA 2. NADTINADH + H+ • For both: Give full name (if you copy the formula from an Internet source, please cite it properly, for example, according to the Chicago Manual of Style. • Indicate what are the chemical groups that are active in these molecules, i.e., what group participates in metabolic reactions (be aware that both molecules may be involved in both anabolic and catabolic processes). • What vitamin or vitamins will, when modified, contribute to the structure of these molecules? • Write a short, general conclusion of the importance of these two coenzymes in metabolism.

Please answer all.

Answer 1

NAD⁺ - Nicotinamide adenine dinucleotide

Nicotinamide is the chemical group active in this molecule. It is the water soluble amide form of vitamin B₃. NADH is basically the reducing power of the cell and is involved in redox reactions. It plays the role of electron acceptor in the metabolic process.

Acetyi CoA - Acetyl Coenzyme A

Acetyl is the main chemical group active in the molecule which is oxidized for energy production. Beta-mercaptoethylamine group is part of Coenzyme A which is linked to the vitamin pantothenic acid. Acetyl CoA is involved in the link reaction during cellular respiration which forms a link between the Glycolysis and Kerb's cycle.

Acetyl-CoA - - P-0 해애ㅇ 해 0 Oft an + oH -lo NADT - Rib - ADR