Question

3. While our genetics play a large role in determining our phenotype, the environment does as well. This concept is well demonstrated when looking at the coat coloration on Siamese cats. How has the environment impact their coat color? 4. Achondroplasia is a common cause of dwarfism in humans. All individuals with achondroplasia are thought to be heterozygous at the locus that controls this trait. When two individuals with achondroplasia mate, the offspring occur in a ratio of 2 achondroplasia:1 normal. What is the most likely explanation for these observations?

Answer 1

1. While ouer gewekce play a large role determing our phenotype, the environment does as well. The phenotype of an individual is influenced by the external environmental ochons such as temperaturo", availability of nutrients, light, drugs and chemicals etc as well as by internal onwronmental factors such as hormones and metabolisms The coat coloration of Siamese cat is affected due to temperature. These cats show's pigmentation at the extremities such as ears fails and paws. The gene that codes for a temperation sensitive enzyme causes these dark points on these siamese cats, and this enzyme is active only in the coder parts of the body. This phenotype of having dark points is called pointed and the pointed pattern is a form of partial albinism, which occurs due to mutation in an enzyme concerned with p melawn production. This mutated enzyme being heat sensitive is active in cooler parts of cat's body and fails to work at normal on higher body temperature.

trans autosomal lisease is dominant al 2. Achondroplasia is a genetic disease of cartilage which is transmitted on an autosomal dominant Otrant. The disease is because of disturbance of costilage mediated Cendechon doral) bone formation. It is considered to be the most common form of devantiem in humans. Achondroplasra is caused by watabone of the game cedang fibroblast growth fadern secephone's (Farr 3) " localed out louberova Upls. 3.FG FR3" is the kay mgalis regulator of andechon dual consideration, and a you of function' melion exagerates the megative sregulation mutati qene coding libroblast ar actor receptor 3 end cel bun derecho do great plade cordoghes , sadulse in the cellular hypert porthophy Howeve ano artilage matrix po roduchun, han de se conto de la natura para o due to developme fait le gou a fully bitony and are When two individuals with achondroplasia (Oddmate oll-springs are : & Dddd | d Dd Idd & D d D IDD Dd Where Dd- individual with achondroplasia dd - normal DD. lethal The most affected offspring are heterozygous cohich suggests that the genotype with homozygous dominant (D) is lethal and hance the ratio is 2 achondroplasia: I nommat.
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