To eliminates the action potential which is + 35mV, we need to pump more sodium ions outside for this we need to activate Na+- K+ channel while block sodium or potassium channel so that no potassium enter into cells and hence more positive ions could accumulate outside of cells then inside and hence more positive potensial outside compared to inside of cell membrane.
Hope it's clear..thanks
How would you alter sodium and/or potassium voltage-gated channels to preserve their dependence on voltage, but...
could you please explain how you did each one 5. Draw a graph showing what would happen to resting membrane potential over time, if the sodium/potassium pump were not functioning. How would this affect a neuron's ability to produce action potentials? What does this imply about the quantity of ions that normally cross the membrane during the course of an action potential? (Group D). Topic 2: Action potential conduction and synaptic transmission 6. How would you alter sodium and/or potassium...
choices for A: Na+/K+ pumps, voltage gated K+ channels, voltage gated Ca+ channels, voltage gated Na+ channels choices for B: bidirectionally, unidirectionally choices for C: Na+/K+ pumps, voltage gated K+ channels, voltage gated Ca+ channels, voltage gated Na+ channels choices for D: Na+/K+ pumps, voltage gated K+ channels, voltage gated Ca+ channels, voltage gated Na+ channels Consider this graph illustrating the generation of an action potential across the plasma membrane of a stimulated neuron. +40 ACTION POTENTIAL plasma membrane potential...
3. Many neurons contain "delayed K channels". Like voltage-gated Nat channels, these voltage-gated K+ channels open in response to a rise in membrane potential and then undergo inactivation. However, opening of the voltage-gated K channels lags behind opening of the voltage-gated Na channels. a) Why does neuronal function require the voltage-gated K channels to open more slowly than the voltage-gated Na channels? b) Compared to a neuron that lacks voltage-gated K channels, what differences would you expect in the shape...
An action potential does not move back wards in the axon because.. a.Voltage-gated sodium channels behind the action potential are inactivated. b. Potassium leak channels no longer let potassium ions through c. Voltage-gated sodium channels are open d. Mechanically-gated channels prevent outflow of sodium e. Voltage-gated potassium channels are closed
ana ion channels. The two ions in questions are Na+ (sodium ion) and K+ (potassium ion). The on channels/pumps are a) voltage-gated sodium channel, b) voltage-gated potassium channel, and c) sodium/potassium pump. a) Depolarization: b) Repolarization: c) Restoring ion concentrations:
A mutation causes the incorporation of fewer voltage-gated sodium channels into the membrane of a neuron. a) What effect will this mutation have on synaptic potentials if this neuron receives excitatory input? b) What effect will this mutation have in the axon hillock area?
Action potentials do not occur in the soma of a neuron because a.it lacks voltage gated sodium channels b.it lacks leaky potassium channels c.it lacks leaky sodium channels d.it lacks chemically gated channels
a. what effect would have the blockade of voltage gated Na+ channels? b. what effect would have the opening of chemically-gated Cl- channels? c. what effect does voltage and chemically gated have in common? d. what final effect do you expect to see when either local or general anesthetics are administered?
You are studying the permeability on Voltage-Gated Sodium Channels involved in action potential generation. Predict what would happen to the permeability of Sodium in the following cases (would it decrease, increase or stay the same?). Explain why you chose your answer. i.Increased receptor number. ii. Add a drug that make channel stay open longer. iii. Raise Vm above+35mV. iv.Lower Vm below -70mV. v.Add a drug that prevents channel opening. vi. Add more Na+ to the extracellular environment.
Assume a mutation of the gene coding for the voltage-gated sodium channel resulted in channels that do not have the ball and chain part of the protein. Which of the following would you expect to see? a. A change in the ion selectivity of the channel of the mutated channels, allowing ions other than sodium to move through it. b. A change in the voltage sensitivity of the channel so that it does not open until more depolarized voltages. c....