Question

Leader name 4. Methanol is a highly poisonous solvent, chemically similar to ethanol (alcohol) and similar in appearance and scent. In the US, methanol poisoning is most likely to occur from Ingestion of windshield wiper fluid or other household or industrial products. Poisoning can also occur from drinking adulterated alcoholic beverages Methanol is broken down to formaldehyde by alcohol dehydrogenase (ADH), and then the formaldehyde is broken down to formic acid by aldehyde dehydrogenase (ALDH). Formic acid is highly toxic and can lead to blindness or death. One treatment of methanol poisoning is administration of large amounts of ethanol (alcohol). As the public service poster for travelers in East Asia points out, ethanol will give you more time to seek medical help. Use a separate sheet for your answer.. a. Write out the pathway of methanol metabolism. b. Why would alcohol be an effective treatment for methanol poisoning? Mint, look back at the pathway for alcohol metabolism in Question 3.

Answer 1

Ans) attaching image

b. Ethanol acts as a competitive inhibitor and binds effectively so ethanol is processed first before methanol in the liver. Ethanol inhibits the enzyme alcohol dehydrogenase by binding to it and prevents formation of the toxic compounds.

Alcohol dehydrogenase formaldehyde genose to-formyl tetrainy dro folate Synthase Methand CotH2O formaldehyde formic and Ethanol or antizol

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