17. Researchers have isolated a PFK-1 mutant in which a serie di ve HUWU 4,0 bisphosphate...
17. Researchers have isolated a PFK-1 mutant in which a serie di ve HUWU 4,0 bisphosphate binding site has been replaced with an aspartate. This results in absolutely no binding of fructose 2,6-bisphosphate and a decrease in glycolysis activity. Explain why the fructose 2,6-bisphosphate would no longer bind. 1 mark