Question

Could the characteristic followed in the pedigree in the attachment be caused by an autosomal dominant disease? Why or wh NO
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Answer #1

Answer : D. No, the offspring of I-1 and I-2 contradict an autosomal dominant inheritance.

Explanation :

Traits that exhibit dominant gene action are = 1. Affected individuals have atleast one affected parent. 2. Phenotype will appear on every generation. 3. Two unaffected parents only have unaffected offspring

In this case I-1 and I-2 are not affected but they're offspring are affected so the pedigree is not caused by an autosomal dominant disease.

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