Question

Given two initial chromosomes ABCDEFGHI and LMNOPQRST, what chromosomal rearragements occured to produce the following chromosome? Check all that apply. LMNOSTEFGHI a. deletion O b. duplication O c. inversion Od translocation

Answer 1

1.Option a and d

Deletion and translocation

in the chromosome LMNOPQRST,PQR is deleted and From ABDCEFGHI, EFGHI is translocated into LMNOPQRST

2.Option a,b,c,d

From ABCDEFGHI , GHI is Translocated

In LMNOPQRST, There is inversion LMNO as LONM (An inversion is a chromosome rearrangement in which a segment of a chromosome is reversed end to end)

PQ is Duplicated & RS is deleted

3. monosomic-23(H)-Monosomy is a form of aneuploidy with the presence of only one chromosome from a pair

monoploid-12 (C) 2n=24 , n=12

triploid-36 (G) 3n = 36

nullisomic-22-(B) Nullisomy is a genome mutation where a pair of homologous chromosomes that would normally be present is missing

Trisomic-25-(I)A "trisomy" means that the baby has an extra chromosome

Tetraploid -48(D)-4n = 48

Double trisomy-26 (E) -2n+2 (Double aneuploidy leading to trisomy and/or monosomy of 2 different chromosomes arises because of 2 meiotic non-disjunctional events)

Tetrasomy-26(E) 2n+2 )Tetrasomic - the gain of an extra pair of homologous chromosomes; individuals are called tetrasomics and their chromosomal composition is 2N+2. )

Q4.Option C-Male meiosis 1

Here the disease is x linked recessive .The son born with klinefelters syndrome is having normal vision.this suggest that the inherited x chromosomes are not due to disjunction of maternal x chromosome.So nondisjunction occured in paternal chromosome.That is XY chromosome of father Failed to segregate and transmit to child.

(If XX from maternal chromosome segregated to the child,child will be colour blind)

Also,Splitting of Paternal chromosome occur during meiosis 1,Here The splitting dont occur in paretnal chromosome & It transmit to child as XY