Question

4. Consider the Figure below. Based on the information flow, state the NULL hypothesis and interpret the results of the study. Cytochrome P4501A is Phase I detoxification enzyme that is activated upon carcinogen exposure. Provide the reasonable mechanistic explanation as to why there are two different physiological outcomes upon carcinogen exposure. (10 pts) H ORA Mutation Carcinogenesis

STATE NULL HYPOTHESIS

EXPLAIN MECHANISTICALLY THE DIFFERENT OUTCOMES

Answer 1

NULL HYPOYHESIS-in statics this null hypothesis was dentoted by Ho,or H-nought.it is a default statement and no relationship between two measured phenomenon .importance of null hypothesis-they provide an approx description of the phenomenon ,nullhypothesis is the one which is conducted by testing for examaple taking mean of the given data ,null hypothesis is not theoritical but it is a tested data and their value is sometime much approx to the original answer.null hypothesis is a precise statement.,usually we relate null in terms of zero but sometime the value of null is more than zero,such as 0.5,0.9 etc.,for example the correlation between frustration and aggresion is 0.5... null hypothesis play an important in testing the significance of differences in experiment and between observations.