Question

1. In the introduction section the authors wrote "Mitochondria are important organelles in the metabolism of all cells, particularly in neurons because of their high energy demand 11." What do neurons need energy for? In other words, what do they do that requires energy? (1 point) 2. In the introduction section the authors wrote Dysfunctional and damaged mitochondria lose their membrane potential, leading to activation and accumulation of PARKIN and degradation of the whole organelle 17, 8]." What is the charge of a mitochondrion that doesn't have membrane potential? (1 point) 3. How do you know that your answer to question 2 is correct? (1 point) 4. In the introduction section the authors wrote "Because the circadian clock controls many of the abovementioned processes (11-13]. the non-motor symptoms of PD might be a consequence of circadian clock malfunction and not a direct cause of the disease. Which processes did the authors say the circadian clock controls (1 point) 5. In the introduction section the authors wrote "Per and time expression is activated at the end of the day and at the beginning of the night by CLK/CYC transcription factors, acting as heterodimers. What exactly are CLK/CYC doing? (1 point) 6. Where are CLK/CYC doing what they are doing? (1 point) 7. How do you know that your answers to questions 5 and 6 are correct? (1 point) 8. What do PER and TIM do to CLK CYC? (1 point) 9. Quote something from this article as evidence that your answer to question 8 is correct. (1 point) 10. In the locomotor activity rhythm and sleep analyses section of the material and methods section the authors wrote "In LD 12:12 and DD. the rhythm of locomotor activity was also examined, and the period of the circadian rhythm was estimated in DD." Why did the authors test Drosophila in LD and then in DD? (1 point) 11. In the effects of all and park mutation en lifespan and behavior section of the results section the authors wrote "The lifespan analysis of mull" and park' mutants showed that both mutations significantly reduced longevity up to 30% and 25% in mull" and park' respectively (Fig. la)." Why was longevity reduced? (1 point) 12. Quote something from the article as evidence that your answer to question 11 is correct. (1 point)

Answer 1

ms 1. Newwns are smallest unit of brain Borain is that structure of body that control all the parts of body. → Neuron communicate to each other by sending Signal and fire action potential. ATP is used by newions to perform various biochemical sxn, Brain consume most enegy To pump ion across memberane, to generate action potential so that signal can be Communicated So require energy Scanned with CamScanner