Explain why sporadic cancers better fit Knudson's Two hit hypothesis than familial cancers.
Knudson Two hit hypothesis tells about the mutations in the tumor suppressor genes which leads to cancer, at the cellular level mutations in the tumor suppressor genes are recessive but in the families having cancers due to mutations in the tumor suppressor genes, the inheritance shows dominant inheritance. In Familial cancers, the parents the individuals in the family can carry the gene which is responsible for the Cancer, so if the individual who is carriers of the mutation requires only one hit in another gene to become cancerous.
Whereas in sporadic cancers there is no family history of the disease, that is individuals are not carriers of the mutation, cells in them require hit in both alleles to become cancerous, so sporadic cancers better fit Knudson's Two hit hypothesis than familial cancers.
Explain why sporadic cancers better fit Knudson's Two hit hypothesis than familial cancers.
Clarify if sporadic or familial cancers fit the Knudson’s Two hit hypothesis and why? I know it is sporadic but why?
Why is it better to use a linear fit to extract k instead of calculating it from a single value?
Explain why multiple extractions with smaller volumes of the extraction solvent are typically "better" than single extractions with a larger volume of the extraction solvent.
What is Knudson’s Two hit hypothesis? And what is the general message?
3. (5 points) Explain why a first price auction is likely to perform better than a second price auction when bidders are experienced but risk-averse.
Briefly explain why rough measurements might yield results with better precision than measurements done in a more exact fashion
why plavix is better than aspirin?
why is longer password a better security mechanism than a better encryption?
Can someone please explain a better approach other than to test that the intercept was equal to zero and that the slope was equal to one? Is there any other hypothesis test one can perform for the slope and intercept?
10) (a) In a hypothesis testing procedure explain the difference between a type 1 and type 2 error (b) Explain the difference between a point estimate and an interval estimate? What is a confidence interval? (c) A poll service indicates that 74% of the public is opposed to a certain piece of legislation but there is a 95% margin of sampling error of 3.1%. Express these findings as a confidence interval. (d) You read in the paper that in a...