8. Which subtype(s) of breast cancer will most likely be treated using Herceptin?
Select 1 or more:
a. HR-, HER2+
b. HR+, HER2+
c. HR-, HER2-
d. HR+, HER2-
8. Which subtype(s) of breast cancer will most likely be treated using Herceptin? Select 1 or...
JK is a 48 yo premenopausal women recently diagnosed with breast cancer. She weighs 150lbs and is 65 inches tall. Basic metabolic labs are normal. The cancer tumor measures between 2 and 5cm and found in 1 to 3 axillary lymph nodes. Her cancer is HER2 positive, ER positive, and PR positive. 1. JK’s cancer is most likely to be classified as (give the stage)? ________ 2. Since her cancer is HER2 +, which medication would she most likely be...
Herceptin can be used to block hormone receptors on HER2+ cancer cells. Select one: a. True b. False Jess has been diagnosed with cancer at the age of 42. Further testing reveals that their healthy cells have Select one: a. mutations in growth factor genes O b. an inherited oncogene c. an inherited mutation in a DNA Repair Gene d. a chromosome pair with inherited mutations in a TSG
(F.1) Find the most recurrently mutated genes in breast cancer (using this dataset Breast Cancer (MSK, Cancer Cell 2018) in cBioportal )? (F.2) Anything different about the different subtypes (using Overall Patient Receptor Status to group patients)?
22. My friend, Marina, is keeping her HER+ cancer from growing by using Herceptin that is attached to a cytotoxic, antineoplastic drug. Thus, where Herceptin alone was not working, she is now successfully using Herceptin ______________. a. in a conjugated monoclonal antibody form. b. to deliver PD-1 inhibitors to each cancer cell. c. to target all actively dividing cells. d. to unleash cytotoxic T cells.
1. [ ] can be used to [ ] hormone receptors on HR+ cancer cells. a. SERMs, activate b. Herceptin, block c. Herceptin, activate d. SERMs, block
We have a population of 100 breast cancer patients of which half have received some form of treatment (i.e. chemo, radiation, etc). Use this information to answer the following questions a. If X represents the number of breast cancer patients who have received treatment in the sample, what distribution it follows? b. If we sample 10 patients, how likely will 4 have received treatment? c. If we sample 25 patients, how likely will 5 have received treatment? d. If we...
Which of the following variants are most likely to be subject to negative selective pressure? (select two answers) a variant at the HEXA gene that leads to Tay-Sachs disease, a fatal childhood neurodegenerative disease a variant at the APOE gene that causes Alzheimer’s disease, an adult-onset neurodegenerative disorder a deletion on the Y chromosome with no health consequences except for a decrease in fertility a variant in the BRCA1 gene that leads high risk of developing breast cancer from the...
1. What are Newly Industrializing Economies (NIEs)? 2. Which woman would be most likely to benefit from genetic testing for breast cancer? O a 25-year-old woman whose mother, aunt, and grandmother had breast cancer O a healthy 75-year-old woman with no family history of breast cancer O a 40-year-old woman who has a cousin with breast cancer 0 a 55-year-old woman whose older sister was just diagnosed with breast cancer All women can benefit from genetic testing for breast cancer.
6941 - Which of the following patients is most likely to be treated with a pneumatic anti-shock garment (PASG)? Select one: A. A 45 year old woman whose pelvis and legs were pinned by a fallen tree for 30 minutes B. A 53 year old man who was kicked in the chest by a horse and complains of dyspnea C. A 14 year old girl in cardiac arrest with multisystem trauma D. An 18 year old man who struck his...
5. I ncreased activity of which of the following is most likely to cause cancer to form? a. a poptosis b. density-dependent inhibition c. kinetochores d. oncogenes e. tumor suppressor genes