Question

Which of the following is a correct description of a disease process encountered in this section?

a.	In Tay-Sachs disease, gangliosides are not produced in sufficient quantity
b.	Many viruses and some bacterial toxins bind to membrane glycolipids.
c.	Cardiocvascular disease generally results from too many LDL particles being endocytosed into liver cells.
d.	Hyperlipidemia is generally caused by too many LDL receptors on the liver cell membranes.

Answer 1

option(b) is correct

1. Tay sachs disease is caused by a genetic mutation in the HEXA gene encoding an enzyme beta-hexosaminidase on chromosome 15 which results in the accumulation of GM2 ganglioside, causing toxicity within cells.

2.Simian virus 40 (SV40), a nonenveloped DNA virus of the papova (papilloma and polyoma) virus family uses glycolipids as a cell surface attachment site and bacteria Vibrio cholerae toxin AB5 binds to ganglioside for entering into cells

3.Cardiovascular disease is usually associated with the deposition of fatty acid in the arteries leading to an increased risk of blood clots

4.Hyperlipidemia means high level of LDL (bad) cholesterol in blood. This condition leads to increased fatty acid deposits in arteries and the risk of blockages.