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What are the protein amino acids modified during N-linked glycosylation? What are the steps involved in...

What are the protein amino acids modified during N-linked glycosylation? What are the steps involved in the addition of the en masse carbohydrate complex to a protein and its modification in the ER?

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Answer #1

n-linked glycolysation :

all the N_LINKED CARBOHYDRATES are linked through N-ACETYKGLUCOSAMINE and AMINO ACID ASPARGINE -it starts with addition of 14-sugar precursor with asparagine amino acid

-CARBOHYDRATES are attached to PROTIEN IN TWO WAYS :N_LINKEd and o-linked GLYCOLYSATIOM

carbohydrates are attached to protiens by nitrogen or oxygen.

MODIFICATION IN ER:

n-linked glycolysation begins in ER

path taken by polypeptide through secretary pathwat starts with its translocation across or into ER membrane.

it must be folded andmodified correctly in ER before being transported via golgi apparatusto cell surface and futher destinations.

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