Question

Answer both a and b. The genome of the bacteria E. coli is 5.4 X 106 nucleotides long. Replication of the DNA here is 500 nucleotides/second. Replication is bi-directional from the single origin, so each fork copies ~ half of the DNA and the two forks probably get done at about the same time. a. How long should it take (in minutes) for replication to be completed in E. coli? The haploid human genome is 3 X 109 nucleotides long, but it is divided into 23 chromosomes so each chromosome averages 1.3 X 108 nucleotides. Here, DNA is replicated at 50 nucleotides / second. b. How long (in hours) will it take to copy a human chromosome if there is but one origin? Remember replication is still bi-directional.

Answer 1

solution.

Both answer are given and calculated in following image.

solution genem complet al a) size of E. coli Genome is 5.4 x 106 nta 5400000 nt , speed of Replication is Replication is bidirectional so it will gon take Har time to complek Replication of complet Time - 5400000 to x 1 - 5400 at seeard 5400 sec = How many minute = 5900 - go minut Required to 6o see see complete replicata 6 size a Human chansosome is 130000000 at speed a Replication is sont/ sec. Replration is bidirectional so it will also take that time to complete "Replicahas g 13x108 af. Time - 130000000 eet - 13000 co see 50 2 1300000 see mean How may Hrs 1300000 = 361.11 Hr Required to - Complete replication g singh chanosine 60x60