Homework Answers
1. Serum Phenytoin is highly protein bound and will bind to serum proteins and will not have pharmacological effect. The therapuetic effect is by the free phenytion in the serum.
2. As free serum phenytoin i.e., unbound to any proteins in serum is the therapuetically important and estimating the levels will help to understand the effect on the seizures.
3. Diarrhea is also a side effect of prolonged use of phenytoin. However stool test or ecoli test is also important to find out the exact reasons for diarrhea. details about other medications and low white blood cells perhaps are the other tests done to find the reasond for the diahrrea.
4. free phenytoin concentration is low or dosage is not sufficent.
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