Question

I only got partial credit on this question, but for future reference I am wondering what I missed or got wrong? Thanks for the help!

Select all of the modifications from this list that can occur co- translationally Removal of the signal sequence by proteolysis N-linked glycosylation Proteolysis of proinsulin to form mature insulin O-linked glycosylation Prenylation of a Rho GTPase Phosphorylation of a protein by a kinase Dephosphorylation of a protein by a phosphatase Activation of PKA by CAMP Polyubiquitylation of a misfolded protein

Answer 1

answer:

Co-translational protein modification. : it is a process of covalentl alteration of amino acids in a protein after initiation of translation but before release of the protein from the ribosome.

these are the modifications occurs during cotranslational modifications:

1. N-LINKED GLYCOSYLATION :

• protein folding and cellular attachment

• attachment of an oligosaccharide (glycan) to a nitrogen atom.

• The synthesis of N-linked glycan begins in the endoplasmic reticulum further continued  in the Golgi and ends at the plasma membrane, where the N-linked glycoproteins are either secreted or becomes embedded in the plasma membrane.

all other options occur during Post translations modification.