Question

- Microson Word - introloCrystax a Search Textbook Solutions the x + is.vtedu can not auctor 1900 znako Question 1 1 pts OE 103 100 105 - 150 oooooo 1917 251 125 1303210 94 120 279 100 10153120 This is one part of a pedigree for Thrombocytopenia in King Charles Spaniels. Because breeding in dopts does not follow taboos we see in humans, crosses between siblings are not uncommon Notice dog 249 is sire to both 150 and 28. Likewise, dog 48 is site to 49 and 271. The pointed connector between 49 and 124 indicates siblings. Looking at this pedigree, what would you say is the most likely mode of inheritance? Autosomal recessive Autosomal dominant X linked recessive X-linked dominant Question 2 2 pts o search o Hie a oo

Answer 1

Mode of inheritance should be Autosomal recessive as the two phenotypically normal parents (121 and 103) are having diseased offspring (82) which is only possible when parents are both carrier to disease.

Further in case of 249 and 28 female is diseased and male is showing normal phenotype. Among there offsprings female is affacted which is only possible when male is carrier to disease. Male may be carrier only in case of autosomal traits.

Hence inheritance pattern should be Autosomal recessive.