Question

Describe the structural features of the renal corpuscle that enhance its blood filtering capacity include in your answer the following terms: pedicels, podocytes, filtration slits, fenestrated epithelium, the diameters of the afferent and efferent arterioles 1. 2 A clinical question. Predict the effects on levels of aldosterone and ADH of each of the following a. Hemorrhage b. Increased permeability of the endothelial-capsular membrane .Excessive loss of body water by sweating A clinical question. Joyce, an accident victim, was admitted to the hospital 3 hours ago. chart indicates that she had been hemorrhaging at the scene of the accident. Joyce's nurse monitors her uninary output and notes that it is currently 12 ml/hour. (Normal output is 30-50 ml/hour) Explain why a person in such severe stress is likely to have decreased urinary output (oliguria). Her 3.

Answer 1

A renal corpuscle is the blood filtering component of the nephron of the kidney. It has two components - the glomerulus ( a tuft of capillaries formed by the afferent arteriole) and the Bowman's ( or glomerular) capsule ( the double walled epithelial cup that encloses the glomerulus).

The glomerulus capillary membrane is similar to that of other capillaries, except that it has three layers ( instead of two) : the fenestrated endothelium, a basement membrane and a layer of epithelial cells called Podocytes surrounding the outer surface of the capillary basement membrane. Podocytes have foot process, pedicels, that wrap around glomerular capillaries. The one pedicel is integrated with another pedicel of adjacent podocyte forming filtration slits.

Blood plasma is filtered in the glomerular capsule, and then the filtered fluid passes into the renal tubule.