Question

Hennophile Balled the royal disease" bechuselmany European royal families had members with the condition. Hemophilia is processive, X-linked disorder. Queen Victoria was unaffected by hemophilia, but was a carrier of the hemophilia gene xx. Suppose: Queen Victoria's husband, Prince Albert, was affected with hemophilia (XY What is the percent probability that a son of Queen Victoria and Prince Albert would be unaffected by hemophilia DESERRIR probabilay of unaffected some SETTO What is the percent probability that a daughter or son of Queen Victoria and rince Albert would be affected by hemophilia? probability of affected child 000 What is the percent probability Queen Victoria and Prince Albert would have one atfected male and probability of one affected male and the one affected female:

Answer 1

Genotype of the Queen Victoria = xH xh Cenotype of the Queen Victoria's husband = X Y Following genotypes are possible: xH xH = normal female xH xh a noomal but carier female xh xh = affected female xHy = Normal male thy - Offected male Hemophilia is a recessive, X-linked disorder, Now, the cross between Queen victoria and her husband . coill be like : Parents > xH xn xxhY gemetes e Peng Ch e ng olipoings . xxh Xhy xhxh XhY camier nomal affected affected Yem de male female male Son of Probability that Queen victoria and prince Albert i would be an affected by hemophilia = 1 £ [XHy] or 50%.

- Probability that daughter off or son of Queen I Victoria and Albert prince Albert could be - affected by hemophilia = į h [xhxh and X²Y] or 50%. Albert one Probability that Queen Victoria and prince would have one affected male and then affected female = txt a to = 6.25.

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