23. Propose an alternate Williamson ether
synthesis reaction that forms the same product.
Homework Answers
Summary : Above are the Alternative method for the ether Synthesis by using Diazotization reaction followed by nucliophilce substitution reaction to get an desired ether as an final product.
Add Answer to:
23. Propose an alternate Williamson ether
synthesis reaction that forms the same product.
OH NaOH I...
e) Typically. Williamson ether synthesis is conducted using Na, a very strong base in the reaction...
e) Typically. Williamson ether synthesis is conducted using Na, a very strong base in the reaction in d. however, the Williamson ether synthesis was accomplished with K.CO a much weaker base Why can K.CO, be used for this Williamson ether synthesis? n What general type of reaction is occurring here? g) Predict the reagents, then propose a mechanism (Hint: don't reduce the ester) OCH,
please answer these questions. thanks 1. Write a reaction of the Williamson Ether synthesis of your...
please answer these questions. thanks
1. Write a reaction of the Williamson Ether synthesis of your product. 2. In this acid catalyzed reaction, a stable benzylic carbocation is formed. Show how this carbocation is formed. 3. Write resonance forms for the benzylic carbocation that is formed. 4. Use the government website www.uspto.gov to find the patent number for the synthesis of your product. Step 2: Ether Synthesis он OR NaBH ROH Amberlyst-15 NaoH H,O он он он
This is a williamson ether synthesis SN2 reaction. what are the complete mechanisms of this reaction,...
This is a williamson ether synthesis SN2 reaction. what are
the complete mechanisms of this reaction, with the intermediates
included?
MLNVILI SYNTHESIS OF 2-BUTOXYNAPHTHALENE OH 1. NaOH, ETOH 2. n-BuBr DISCUSSION: Nucleophilic substitution reaction is a frequently used method to convert one functional group into another. A nucleophile is mixed with an electrophile and the nucleophile replaces the leaving group to produce a new compound. In this experiment, a weak nucleophile (2-naphthol) is converted into a strong nucleophile. Then this...
Could the Williamson Ether synthesis be carried out using any type of alkyl halide? Why/why not....
Could the Williamson Ether synthesis be carried out using any type of alkyl halide? Why/why not. Draw the mechanism for the Williamson Ether reaction using bromoethane and t-butyl bromide and relate it to your answer.
The Williamson ether synthesis between 2‑naphthol (MW 144.2 g/mol) and allyl bromide occurs in dichloromethane solution...
The Williamson ether synthesis between 2‑naphthol (MW 144.2 g/mol) and allyl bromide occurs in dichloromethane solution in the presence of the phase transfer catalyst, PhCH 2 ( Bu ) 3 NCl , and NaOH and produces allyl 2‑naphthyl ether (184.23 g/mol). A reaction was performed in which 0.43 g of 2‑naphthol was reacted with a slight excess of allyl bromide to make 0.46 g of allyl 2‑naphthyl ether. Calculate the theoretical yield and percent yield for this reaction. Allyl bromide...
How would you prepare benzyl methyl ether using a Williamson ether synthesis? The list of reagents...
How would you prepare benzyl methyl ether using a Williamson ether synthesis? The list of reagents to choose from are: 2-Chloro-norborane, Benzyl chloride, 2-Chloro-2-methylpropane, 4-Chloro-1-butanol, and Chlorobutane. I was reading online and it kept mentioning SN2 reactions, using an alcohol, and an alkyl halide for the synthesis. My guess would be using Benzyl Chloride and another one with an OH attached, but I could be completely wrong. Please help and explain by showing the reaction mechanism. Thank you so much!...
4. (3p) Write the product for the following reaction: NaOH CHO 5. (3p) Propose a synthesis...
4. (3p) Write the product for the following reaction: NaOH CHO 5. (3p) Propose a synthesis for the following compound by using a Witting reaction:
Williamson ether syhthesis involves a SN2 reaction between an alkoxide generated in situ and a primary...
Williamson ether syhthesis involves a SN2 reaction between an alkoxide generated in situ and a primary or secondary halide. Determine the chemical Reaction/Mechanism of the Sn2 reaction: using para-ethyl phenol and 2.5 mL of 25% aqueous NaOH. When the reactant is completely dissolved, add 150 mg of the phase transfer catalyst (tetrabutylammonium bromide) followed by additional of the unknown electrophile, methyl iodide.
1. Which reagent could be used in a Williamson Synthesis of cyclohexyl methyl ether? H2SO4, NaCl,...
1. Which reagent could be used in a Williamson Synthesis of
cyclohexyl methyl ether?
H2SO4, NaCl, H2O, or NaH
-----------------------
2. Which carboxylic acid is the most acidic?
---------------------
3. A reaction that would give n-hexyllithium is:
CH3CH2CH2CH2CH2Br + 2Li
CH3CH2CH2CH2OH + Li
CH3CH2CH2CH3 + Li
CH3CH2CH2CH2Br + LiBr
CH3CH2CH2CH3 = CH3Li
----------------------
4. Starting with p-bromoanisole, what sequence of reactions will
produce p-methylanisole?
1. CH3l 2. Mg, ether
1. Mg, ether 2. CH3l
1. Br2, AlBr3 2. Mg, ether...
4) Briefly explain why the following molecule cannot be produced using Williamson ether synthesis. 4 pts...
4) Briefly explain why the following molecule cannot be produced using Williamson ether synthesis. 4 pts Note: a complete answer will illustrate the two theoretical William ether synthetic pathways that could be used to synthesis the product (1 pt each) and explain why each pathway would not yield the desired product (1 pt each). Bonus: Provide a different synthetic pathway that produces the ether shown above. (I could do it in a single step!). (bonus 2 pts).
e) Typically. Williamson ether synthesis is conducted using Na, a very strong base in the reaction in d. however, the Williamson ether synthesis was accomplished with K.CO a much weaker base Why can K.CO, be used for this Williamson ether synthesis? n What general type of reaction is occurring here? g) Predict the reagents, then propose a mechanism (Hint: don't reduce the ester) OCH,
please answer these questions. thanks
1. Write a reaction of the Williamson Ether synthesis of your product. 2. In this acid catalyzed reaction, a stable benzylic carbocation is formed. Show how this carbocation is formed. 3. Write resonance forms for the benzylic carbocation that is formed. 4. Use the government website www.uspto.gov to find the patent number for the synthesis of your product. Step 2: Ether Synthesis он OR NaBH ROH Amberlyst-15 NaoH H,O он он он
This is a williamson ether synthesis SN2 reaction. what are
the complete mechanisms of this reaction, with the intermediates
included?
MLNVILI SYNTHESIS OF 2-BUTOXYNAPHTHALENE OH 1. NaOH, ETOH 2. n-BuBr DISCUSSION: Nucleophilic substitution reaction is a frequently used method to convert one functional group into another. A nucleophile is mixed with an electrophile and the nucleophile replaces the leaving group to produce a new compound. In this experiment, a weak nucleophile (2-naphthol) is converted into a strong nucleophile. Then this...
4. (3p) Write the product for the following reaction: NaOH CHO 5. (3p) Propose a synthesis for the following compound by using a Witting reaction:
1. Which reagent could be used in a Williamson Synthesis of
cyclohexyl methyl ether?
H2SO4, NaCl, H2O, or NaH
-----------------------
2. Which carboxylic acid is the most acidic?
---------------------
3. A reaction that would give n-hexyllithium is:
CH3CH2CH2CH2CH2Br + 2Li
CH3CH2CH2CH2OH + Li
CH3CH2CH2CH3 + Li
CH3CH2CH2CH2Br + LiBr
CH3CH2CH2CH3 = CH3Li
----------------------
4. Starting with p-bromoanisole, what sequence of reactions will
produce p-methylanisole?
1. CH3l 2. Mg, ether
1. Mg, ether 2. CH3l
1. Br2, AlBr3 2. Mg, ether...
4) Briefly explain why the following molecule cannot be produced using Williamson ether synthesis. 4 pts Note: a complete answer will illustrate the two theoretical William ether synthetic pathways that could be used to synthesis the product (1 pt each) and explain why each pathway would not yield the desired product (1 pt each). Bonus: Provide a different synthetic pathway that produces the ether shown above. (I could do it in a single step!). (bonus 2 pts).
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