Identify the true statements about RNA interference. Select all of the true statements. Duplex RNA is...
Identify the true statements about RNA interference. Select all of the true statements.
Duplex RNA is cleaved by the Dicer enzyme complex.
Duplex RNA (dsRNA) can suppress the expression of a gene.
miRNAs are short, single-stranded RNA segments that are about 45 nucleotides long.
RNA interference can temporarily suppress the expression of a target gene.
miRNAs suppress gene expression by interfering with transcription.
Homework Answers
True. Duplex RN is cleaved by dicer enzyme. Dicer enzymes belongs to RNAse III family that cleaves dsRNA (pre miRNA) into 20-25 b long siRNA and/or miRNA
True. Duplex RNA can suppress the expression of genes by triggering post transcriptional degradation of homologous RNA in the cytoplasm.
False. miRNA are small single stranded that are approximately 22 nucleotides long.
True. RNAi is temporary that can be stabilized by transfecting target tissues such that they express dsRNA autonomously.
False. miRNA inhibit gene expression post transcriptionally bind to the 3’UTR of the target mRNA and destabilize them hence suppressing protein production causing translational silencing.
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Identify the true statements about RNA interference. Select all
of the true statements.
Duplex RNA is...
In the first stage of RNA interference, a __________ RNA precursor is cleaved by the _________...
In the first stage of RNA interference, a __________ RNA precursor is cleaved by the _________ enzyme. The cleaved molecules are approximately _________ (insert number) bases in length and are called ___RNA if the RNA originated from a virus or ___RNA if the RNA was of endogenous origin ( if the RNA precursor was produced artificially, it's called ___RNA. The cleaved RNA is then separated into _____________ RNA, which then binds to the ribonuclease complex called __________. The short RNA...
As indicated in the image below, miRNAs usually have imperfect base pairing with their target mRNAs,...
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Part A Outline the roles of
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check all that apply Which of the following statements are true about the Sherlock protocol: The...
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Which of the following statements are true about the Sherlock protocol: The test requires a lab to run the PCR This test does not require a PCR step The Cas13 protein attached to the RNA guide has collateral RNA activity If the Reporter RNA is cleaved by CAS13 it binds to the test strip, 2 lines will appear test positive Collateral RNAse activity is activated when RNA guide finds the target RNA (COVID19).
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Which of the following statements about pattern formation are true? Select the four statements that are...
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As indicated in the image below, miRNAs usually have imperfect base pairing with their target mRNAs, which leads to translational inhibition (the RISC complex is large, and won't let ribosomes through). On the other hand, siRNAs produced from longer double stranded RNA molecules (e.g. viruses), usually show perfect binding to their target mRNAs, which leads to mRNA degradation by the RISC complex. In 100 words or fewer explain why these two types of inhibitory ncRNAs differ in their mode of...
Part A Outline the roles of
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