Question

be some alcohols undergo rearrangement or other unwanted side reactions when they dehydrate in acid. Alcohols may denydrated under mildly basic conditions using phosphorus oxychloride (POCk) in pyridine. The alcohol reacts with phosphorus oxychloride muc like it reacts with tosyl chloride (Section 11-5), displacing a chloride ion from phosphorus to give an alkyl dichlorophosphate ester (S,2-like step). The dichlorophosphate group is an outstanding leaving group. Pyridine reacts as a base with the dichlorophosphate ester to give an E2 elimination N CHAPTER 11: PROB ' Using proper curved arrow notation and the description above, Propose a mechanism for the dehydration of cyclohexanol by POCl3 in pyridine

Answer 1