Suppose there is a mutation in the c subunit of ATP synthase, such that the glutamate...
Suppose there is a mutation in the c subunit of ATP synthase, such that the glutamate found in the middle of one of the membrane-spanning helices is converted to a valine. What is likely to be the effect on ATP synthesis and why
Homework Answers
The ATP C subunit is found in the transmembrane protein. This subunit used ATP hydrolysis to transport substance along the membrane. When the glutamate amino acid get mutated to valine, the rate of ATP synthesis will decreased. This is because glutamate is an acidic amino acid, which is polar and hydrophilic whereas valine is non-polar and hydrophobic amino acid. Hence, both have different physiochemical properties. Therefore, both amino acid have different nature. Hence, normal synthesis of ATP will be affected .
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Suppose there is a mutation in the c subunit of ATP synthase,
such that the glutamate...
A mutation in human ATPase 6 (which corresponds to E. coll subunit a) from leucine to arginine at...
pls help!!
A mutation in human ATPase 6 (which corresponds to E. coll subunit a) from leucine to arginine at position 156 may allow the movement of protons across the membrane, but not the rotation of the ring of c subunits. How might this possible mechanism affect the function of ATP synthase? Choose two answers Proton binding to subunit c would not be impaired. There would be an uncoupling of proton translocation and ATP synthesis. ATP hydrolysis coupled to proton...
The release of ATP by the beta subunit of the F1F0 ATP Synthase is most directly...
The release of ATP by the beta subunit of the F1F0 ATP Synthase is most directly dependent on: A) The flow of protons from the intermembrane space to the matrix B) The rotation of the c-ring in the membrane C) The passage of electrons along the electron transport chain D) A conformational change in the beta subunit E) None of the above
A representation of the structure of the mitochondrial ATP synthase is presented in Figure 2 of...
A representation of the structure of the mitochondrial ATP synthase is presented in Figure 2 of this document. Notably, the chloroplast version of the spinach ATP synthase is remarkably similar to the mitochondrial version of the ATP synthase, with one notable exception. In the Fo portion of the chloroplast ATP synthase there are 14 "c" subunits. Discuss this noteworthy structural difference in the ATP synthases relative to the values you calculated in parts D and E of this problem. F)...
In an ATP synthase which has 12 copies of the c subunit, how many protons move...
In an ATP synthase which has 12 copies of the c subunit, how many protons move through the enzyme for each one ATP that is synthesized? 44. 4 12. 45. An uncoupler acts by: a. Inhibiting a redox couple b. nhibiting proton pumping complexes. c. nhting oxygen reduction d. Collapsing the proton gradient e. Uncoupling the F and Fo subunits of the ATP synthase GLUCONEOGENESIS The reactions of glycolysis that are replaced by different enzymes in the gluconeogenesis pathway are...
The rotor portion of the ATP synthase is composed of 10-14 subunits called "c subunits." As...
The rotor portion of the ATP synthase is composed of 10-14 subunits called "c subunits." As protons bind the rotor, on the intermembrane space side of the rotor, the rotor turns one subunit worth of distance. If the rotor of ATP synthase is composed of 10 c subunits, how many protons would be necessary to produce 6 ATP molecules?
Q2. The release of ATP by the beta subunit is most directly dependent on: Select ONE...
Q2.
The release of ATP by the beta subunit is most directly
dependent on:
Select ONE option:
1. the flow of protons from the intermembrane space to the
matrix.
2. the rotation of the c-ring in the membrane.
3. the passage of electrons along the electron transport
chain.
4. a conformational change in the beta subunit.
Q3.
What defines the direction of rotation of the c-ring in the F0
complex?
(Select ALL that apply.)
1. Amino acids side chains in...
1. a. In both mitochondria and chloroplasts, ATP synthesis is coupled to electron transport. Which one...
1. a. In both mitochondria and chloroplasts, ATP synthesis is coupled to electron transport. Which one of the following is likely to affect the coupling of electron transport to ATP synthesis in both of these systems? Explain. A) the absence of light B) the removal of oxygen C) leucinostatin, an ATP synthase inhibitor D)a photosystem II inhibitor 1.b. Explain why each of the other answer choices are not applicable to both of the systems.
1.Bacteriorhodopsin is a protein that has 7 alpha helices embedded in the cell membrane. As such,...
1.Bacteriorhodopsin is a protein that has 7 alpha helices embedded in the cell membrane. As such, how many start-transfer and stop-transfer sequences would it need? 7 start transfer sequences, 6 stop transfer sequences 7 of each, in alternating fashion 4 start transfer sequences and 3 stop transfer sequences 7 start transfer sequences 2. The role of GTP hydrolysis by the Signal Recognition Particle during cotranslational translocation to the ER is to release the SRP after docking to the translocon so...
What process uses ATP to create glucose? O ATP synthase electron transport chain O gluconeogenesis O...
What process uses ATP to create glucose? O ATP synthase electron transport chain O gluconeogenesis O citric acid cycle Question 11 (2 points) What would expect to happen in mitochondria that have fewer cristae Increased proton motive force Decreased oxygen usage increased ATP to ADP conversion O No change in mitocondrial funciton Question 12 (2 points) What is one example of when energy molecules/electron carriers are produced during the citric acid cycle? O conversion of succinate to fumarate O addition...
Please explain why as well. 4. On average, how many ATP molecules are synthesized per NADH?...
Please explain why as well. 4. On average, how many ATP molecules are synthesized per NADH? A. 0 B. 1 C. 2 D. 3 E. 4 5. The FADH2 that is produced donates its electrons directly to A. Complex I B. Complex III C. Complex IV D. Coenzyme Q E. Cytochrome C F. O2 6. In the Binding Change Mechanism the 3 conformational states that occur in the F1 subunit of ATP synthase depend on A. interaction with b subunits...
pls help!!
A mutation in human ATPase 6 (which corresponds to E. coll subunit a) from leucine to arginine at position 156 may allow the movement of protons across the membrane, but not the rotation of the ring of c subunits. How might this possible mechanism affect the function of ATP synthase? Choose two answers Proton binding to subunit c would not be impaired. There would be an uncoupling of proton translocation and ATP synthesis. ATP hydrolysis coupled to proton...
A representation of the structure of the mitochondrial ATP synthase is presented in Figure 2 of this document. Notably, the chloroplast version of the spinach ATP synthase is remarkably similar to the mitochondrial version of the ATP synthase, with one notable exception. In the Fo portion of the chloroplast ATP synthase there are 14 "c" subunits. Discuss this noteworthy structural difference in the ATP synthases relative to the values you calculated in parts D and E of this problem. F)...
In an ATP synthase which has 12 copies of the c subunit, how many protons move through the enzyme for each one ATP that is synthesized? 44. 4 12. 45. An uncoupler acts by: a. Inhibiting a redox couple b. nhibiting proton pumping complexes. c. nhting oxygen reduction d. Collapsing the proton gradient e. Uncoupling the F and Fo subunits of the ATP synthase GLUCONEOGENESIS The reactions of glycolysis that are replaced by different enzymes in the gluconeogenesis pathway are...
Q2.
The release of ATP by the beta subunit is most directly
dependent on:
Select ONE option:
1. the flow of protons from the intermembrane space to the
matrix.
2. the rotation of the c-ring in the membrane.
3. the passage of electrons along the electron transport
chain.
4. a conformational change in the beta subunit.
Q3.
What defines the direction of rotation of the c-ring in the F0
complex?
(Select ALL that apply.)
1. Amino acids side chains in...
What process uses ATP to create glucose? O ATP synthase electron transport chain O gluconeogenesis O citric acid cycle Question 11 (2 points) What would expect to happen in mitochondria that have fewer cristae Increased proton motive force Decreased oxygen usage increased ATP to ADP conversion O No change in mitocondrial funciton Question 12 (2 points) What is one example of when energy molecules/electron carriers are produced during the citric acid cycle? O conversion of succinate to fumarate O addition...
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