Question

For blood type, a mom has the genotype I^A i and the father is I^B i. At the Bombay locus (p. 119), mom is Hh and dad is hh. Determine the possible genotypes and phenotypes of the offspring. What is the ratio of AB:A:B:O phenotypes in the offspring?

Answer 1

Answer:

Allele H is dominant over allele h. At least one H allele must be present to express the respective phenotype. In recessive (hh) conditions, all genotype would become O type blood phenotype.

Mom (IAi; Hh) x (IBi; hh) Dad ---Parents

	IBh	i h
IA H	IAIB; Hh—AB type	IAi; Hh—A type
IA h	IAIB; hh—O type	IAi; hh—O type
i H	IBi; Hh—B type	ii; Hh---O type
i h	IBi; hh—O type	ii; hh—O type

AB = 1

A = 1

B= 1

O = 5

The ratio of AB:A:B:O phenotypes in the offspring = 1:1:1:5