NaOH сн. then heat NaOH yer then heat NaOH (CH3),Culi then heat 1. NaOCH Снзон OCH 2. dil. HCI 1. LDA 1. LIATHA 2. Br 2.H30* 1. NaOCH lich, 2.phor 1. NaOCH, OCH, 2. Ph Br 2. CI 3. H30+, heat 1. LDA 1. LDA o 2. 0 CI 3. H3O+ H 3. H3O+
4. Provide the products of each reaction (3pts. 2pts) 1. H30 OCH3 2. NaOCH; CHOH2 OCH 3. Ht, A 4. NaCN 1. LDA 2 Pho 3. H+, A 4 EtMg Br
HOHC H2O OH OH XS CH,Br HO Ag20 1. NaOCH, 2. H30+, no heat нсо. 1) NaOH, H2O (room temp) 2) cold dilute acidic workup
provide the products for the following reactions. (initial reactant is methyl butanoate for all) OCH, 1) NaOH, H,O, Heat 2) H,0* (CH,CH2), NH, heat 1) CH,Mgl (excess), Et, 2) H30* 1) LIAIH, ELO 2) H30* DIBAIH, Toluene, Low Temp. H,0*
4. Provide the products of each reaction (3pts, 2pts) 1. H,O* OCH; 2. NaOCH, CHOH OCH, 3. H, A 4. NaCN 1. LDA 2. Pho 3. H , A 4. EtMgBr
What is the major organic product obtained from the following sequence of reactions? 1. NaOH, H2O 1. NaOCH CHg 1. NaOCH2CH3 2. HO HOCH CH2OH CH3CH2OH CH3CH2OH 3.A H2SO4 OCH CH3 2. CH3CH2CH2Br 2. CH3| 3. H30* 3. H30* 0000 Nm
10. Find the product(s) of the following reaction: 1. NaOCH + 2. H30+ 3. Ethanol
What is the major product obtained from the following reaction: OCH Br NaOCH OCH CH OH BI OCH, 0 1 2 3 What is the major organic product obtained from the following reaction (KOtBu = OC(CH3)31 big bulky base)? 0-Bu 2 KOBU BUCH 0.tBu W08 0-Bu 1 2 3 0 4
4. Provide the products of each reaction (3pts, 2pts) 1. H2O+ OCH; 2. NaOCH, CHOH OCH 3. H, A 4. NaCN 1. LDA 2. Pho 3. H , A 4. EtMgBr 5. Provide an arrow-pushing mechanism for the reaction below, and state how many product stereoisomers are possible (5 pts) NO2 cat. KOH ЕКОН
(10 pts) Predict the major product for each of the following reactions. 2. Ho Br 1. NaOH/Br 2. H,O NaOH/H20 1. NaOCH,CH 2. H,0 1. NaOCH,CH, 2 HO (10 pts) Predict the major product for each of the following reactions. 2. Ho Br 1. NaOH/Br 2. H,O NaOH/H20 1. NaOCH,CH 2. H,0 1. NaOCH,CH, 2 HO