6. Optically pure (-)-2-butanol has the R configuration and [a] = -13.52º. Optically pure (-)-2-iodobutane has...
3. Pure Θ Kaylanoic acid has a specific rotation of-160° (same conditions and temperature as sample above). What is the % optical purity of the sample above ? (0.75 points) 4. 3.5 mg of optically-enriched(-) antibiotic Zachromycin was dissolved in 1.00 mL methanol in a 1.00 mL volumetric flask. The optical rotation was found to be -0.02220 in a 5.0 cm cell. What is the specific rotation? (0.75 points) 5. Calculate the enantiomeric excess and the specific rotation of a...
11. How would you synthesize the following compound starting with optically pure (R)-2-butanol (note: it could require multiple steps)? HCN HC CH 12. Give the product of the following reaction: СНЫBr NASH Page 2
How would you synthesize the following compound starting with optically pure (R) or (S)-2-butanol? 8) How would you synthesize the following compound starting with optically pure (R) or (S)-2-butanol? H CN НаС. CH3 A) (1) (R)-2-butanol + TSCI B) (1) (S)-2-butanolTsCI C) (1) (S)-2-butanol + H2SO4 (heat) D) (R)-2-butanol NaCN/DMSO (2) NACN/DMSO (2) NACN/DMSO (2) HBr (3) NaCN/DMSO
QUESTION 21 How would you synthesize the following compound starting with optically pure (R) or (5)-2-butanol? н CN HzC CH, A. (1) (S)-2-butanol + TSCI (2) NaCN/DMSO B. (1) (R)-2-butanol + TSCH (2) NacN/OMSO C(R)-2-butanol + NaCN/OMSO y ()-2-Butanol H2504 (heat) (2) HBr (3) NaCN/DMSO QUESTION 22 CHOIS
H6.24-Level 2 If an optically pure compound has a specific rotation of-32 degrees, what would the optical activity of its diastereomers be? 0 A -32 degrees OB+32 degrees C Zero degrees Do not know, it would have to be measured
2. The optical activity, measured by specific rotation, of pure (R-malic acid is [a]20D-+27% What is the specific rotation of a mixture of 50% and 50% of (R)-malic acid and (S)-malic acid? What is enantiomeric excess of a sample of malic acid containing both enantiomers that has a [al20D -0% [a]20D-27"; [a]20D-_ 13.5": [a]20D-+ 13.5°
I a Write the stracture of b. (R )-2-butanol, shown below is converted to a chiral iodide by reacting with sodium iodide. Show the mechanism involved in the reaction and state configuration of the chiral product. 2. Show the products of the following reactions and identify the number of possible stercoisomers that can be produced CH, CH,CH- CH, 1.BH, 2. NaOH, H202 3. Cortisone is a natural steroid that can be isolated from the adrenal cortex. It has ant- inflammatory...
3. Benzene reacts with optically pure (R)-2-chlorobutane and AlCl3. Is the product R? S? Racemic? Explain mechanistically.
What observed rotation is expected when a 1.36 M solution of (R)-2-butanol is mixed with an equal volume of a 0.680 M solution of racemic 2-butanol, and the resulting solution is analyzed in a sample container that is 1 dm long? The specific rotation of (R)-2-butanol is –13.9 degrees mL g–1 dm–1. please show all work
After a sample of optically pure (S)-2-ethyl-cyclohexanone is dissolved in an aqueous solution for several hours, a significant loss of optical activity is observed. Explain. (10 pts) (S)-2-Ethyl-cyclohexanone The following aldol reaction occurs readily. Please provide the product. Why can this compound not undergo the final elimination / condensation to yield an enone? (10 pts) 1. LDA 2. H2O+