Question

11 cont. A pedigree involving the Igf2 locus is shown below. Dwarf-sized individuals are indicated by solid square or circle 4 3 2 It is also known that female mouse 3 is homozygous for lgf2* allele. Based on this, please answer the following questions: a. What is the genotype of mouse 5 with respect to the lgf2 locus (2 points)? Igf2*/lgf2 b. What is the genotype of mouse 4 with respect to the lgf2 locus (2 points)? If male 1 is crossed with female 2, what is the probability that the first offspring is a dwarf-sized mouse (2 points)? c. 0

Can you please explain how they got these answers?

0 0
Add a comment Improve this question Transcribed image text
Answer #1

lgf2 gene in mice shows maternal imprinting. this means the allelle of the gene obtained from mother will remain transcriptionally silent while only the father allele will be active. Mice that will inherit the deletion chromosome from the paternal side will be small,but mice inheriting the same deletion from the maternal side will be normal.Thus, a deletion of Igf2 only causes a mutant phenotype when transmitted by the father.

a. the genotype of mouse 5 is lgf2+/lgf2-. The mother is a dwarf (balckened circle, so genotype, lgf2-/lgf2-). Now for the son to be dwarf as well he should recieve one copy of lgf2- from his father as then only he will be dwarf. . But the father is normal size i.e., hetrozygous for the trait. Therefore his genotype is lgf2+/lgf2-, Please understand that this is not sex-linked inheritance, it is simple autosomal inheritance.

b. The mouse 4 is dwarf. He has one copy of lgf2- gene from his father just like his mother has acquired one from her father. This means he is also heterogygous, lgf2+/lgf2-.

c. Both 1 and 2 have maternal copy og lgf2-, which explains why they are normal size, therefore when they have a child, the lgf2- will remain unexpressed and the first child cannot be a dwarf-sized mouse.

Add a comment
Know the answer?
Add Answer to:
Can you please explain how they got these answers? 11 cont. A pedigree involving the Igf2...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions
  • please include work, show punnets squares and legends. thanks 2. A female Drosophila of unknown genotype...

    please include work, show punnets squares and legends. thanks 2. A female Drosophila of unknown genotype was crossed with a white-eyed male fly, of genotype (w = white eye allele is x-linked recessive, W+= red-eye allele is dominant.) Half of the male and half of the female offspring were red-eyed, and half of the male and half of the female offspring were white-eyed. What was the genotype of the female fly?

  • Need 5-9 and number 11 all answered. Thx 5. How can two individuals with brown eyes(B)...

    Need 5-9 and number 11 all answered. Thx 5. How can two individuals with brown eyes(B) have a blue (b) eyed baby? Show the genotypes of the parents and Punnett square to prove your answer. What are the chances of a blue-eyed baby? 6. A homozygous tongue roller (T) is married to a non-tongue roller(t). If they have 5 children, how many of them will be tongue rollers? Use Punnett square to support and explain your answer. 7. Let's imagine...

  • 1.My wife has black color eyes, the dominant trait. All of her family and relatives have...

    1.My wife has black color eyes, the dominant trait. All of her family and relatives have dark eyes too. I have light color eyes (blue), the recessive trait. We are hoping for a blue-eyed baby. What is the probability we will have a baby with blue eyes? What is the probability we will have a baby with dark eyes? 2. In humans, tongue rolling is a dominant trait, those with the recessive condition cannot roll their tongues. Bob can roll...

  • 11. (8 m) Refer to the following pedigree, which traces the inheritance of a biochemical disorder....

    11. (8 m) Refer to the following pedigree, which traces the inheritance of a biochemical disorder. female not affected female affected 0 male not affected male affected a. (2 m) Does this disorder appear to be caused by an autosomal or sex-linked gene? Does this disorder appear to be caused by a dominant allele or by a recessive allele? Explain how you know this. b. (2 m) Fill in the genotypes of all affected individuals. Use A and a to...

  • Vanilla mice! Someone please help. I am having a hard time with this material and want...

    Vanilla mice! Someone please help. I am having a hard time with this material and want to make sure that I am on the right track. "Fur color in mice is under the control of (at least) three unlinked loci... Question 4: (4 points) Fur color in mice is under the control of at least) three unlinked loci. The C gene determines whether melanin is produced at all; the B gene influences the amount of melanin that is deposited in...

  • can i get help with these 2 problems? In the yawncat (a rare hypothetical animal), the...

    can i get help with these 2 problems? In the yawncat (a rare hypothetical animal), the black coat color allele B is dominant to the brown allele b, but the B locus can only be expressed if the animal has an mm genotype at a second gene locus. Animals that are M_are yellow regardless of which allele from the B locus is present. a. A mating between a yellow-tailed male yawncat and a brown-tailed female yawncat produces 16 offspring with...

  • . O . Using Pedigrees to hypothesize patterns of inheritance 5. For each of the pedigree...

    . O . Using Pedigrees to hypothesize patterns of inheritance 5. For each of the pedigree charts on the following page, determine which pattern of inheritance most likely explains the observed pattern of traits in the family shown. Observe the general patterns in the pedigree charts on the following page o males vs females? parents with disease? Compare these patterns with the clues on the previous page to hypothesize a pattern of inheritance Based on this pattern of inheritance, use...

  • 1. Circle, underline or write in all of the homozygous genotypes listed below. og Aa AA...

    1. Circle, underline or write in all of the homozygous genotypes listed below. og Aa AA 2. In pea plants, the dominant allele Pencodes purple flowers and the recessive allele p encodes white flowers. A plant with a pp genotype is crossed with a plant with a Pp genotype. What is the expected ratio of phenotypes in the offspring? Use a Punnett square to justify your answer. (0.5 points) 3. A mother has type A blood and she has a...

  • Choose from these answers for questions 29 - 32: A. 1 B. 1/3 C. 2/3 D....

    Choose from these answers for questions 29 - 32: A. 1 B. 1/3 C. 2/3 D. 14 E. % G. none of the mice F. all of the mice 29. You mate 2 red mice with each other. Of the live offspring, how many would be red? 30. You mate 2 red mice with each other. Of the live offspring, how many would be black? 31. You mate a red mouse with a black mouse. Of the live offspring, how...

  • Can you explain how to do number 4? dominant individual and umail mmetance, hów can one...

    Can you explain how to do number 4? dominant individual and umail mmetance, hów can one differentiaté between a homozygous one who is heterozygous for the dominant trait? (A) By crossing the individuals in question (B) By crossing each individual with a known homozygous recessive and examining the offspring By crossing each individual with a known heterozygote and examining the offspring (C) (D Both B and C If a male hemophiliac (Xhy) is crossed with a female carrier of both...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT